ArticlePloS one2022
Risks for death after admission to pediatric intensive care (PICU)-A comparison with the general population.
Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.
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Who cites it
10 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Effectiveness of Family-Focused End of Life and Bereavement Interventions Across Neonatal, Paediatric, and Adult Intensive Care: An Overview of Reviews.Journal of clinical nursing · 2026Pooled it
- The elements of end-of-life care provision in paediatric intensive care units: a systematic integrative review.BMC palliative care · 2024Pooled it
- Diagnostic and Prognostic Value of Ferritin and Soluble Interleukin-2 Receptor α in Critically Ill Children with Hyperferritinemia.Diagnostics (Basel, Switzerland) · 2026Article
- Trends in unplanned non-surgical paediatric oncology admissions to paediatric intensive care units in England between 2008 and 2022.European journal of pediatrics · 2026Observational
- Beyond Staying Alive….Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies · 2025Article
- Escherichia coli causing bloodstream infections in Mexican paediatric patients: molecular typing, antimicrobial resistance, virulence factors, and clinical features.BMC infectious diseases · 2025Article
- [Incidence of acquired morbidity and its impact on patients in a pediatric intensive care unit based on the functional status scale]Revista de la Facultad de Ciencias Medicas (Cordoba, Argentina) · 2025Observational
- Intensive care risk and long-term outcomes in pediatric allogeneic hematopoietic cell transplant recipients.Blood advances · 2024Article
- Editorial: Insights in intensive care medicine and anesthesiology: 2022.Frontiers in medicine · 2024Article
- Incidence and Mortality Trends in Critically Ill Children: A Korean Population-Based Study.Journal of Korean medical science · 2023Article
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
OBJECTIVE/
aimThe aim of the study was to quantify excess mortality in children after admission to a Pediatric Intensive Care Unit (PICU), compared to the age and sex matched general Swedish population.
designSingle-center, retrospective cohort study.
settingRegistry study of hospital registers, a national population register and Statistics Sweden. PATIENTS: Children admitted to a tertiary PICU in Sweden in 2008-2016.
interventionsNone. MAIN
resultsIn total, 6,487 admissions (4,682 patients) were included in the study. During the study period 444 patients died. Median follow-up time for the entire PICU cohort was 7.2 years (IQR 5.0-9.9 years). Patients were divided into four different age groups (0-28 d, > 28 d -1 yr, > 1-4 yr, and > 4 yr) and four different risk stratification groups [Predicted Death Rate (PDR) intervals: 0-10%, > 10-25%, > 25-50%, and > 50%] at admission. Readmission was seen in 929 (19.8%) patients. The Standardized Mortality Ratios (SMRs) were calculated using the matched Swedish population as a reference group. The SMR for the entire study group was 49.8 (95% CI: 44.8-55.4). For patients with repeated PICU admissions SMR was 108.0 (95% CI: 91.9-126.9), and after four years 33.9 (95% CI: 23.9-48.0). Patients with a single admission had a SMR of 35.2 (95% CI: 30.5-40.6), and after four years 11.0 (95% CI: 7.0-17.6). The highest SMRs were seen in readmitted children with oncology/hematology (SMR = 358) and neurologic (SMR = 192) diagnosis. Children aged >1-4 years showed the highest SMR (325). In PDR group 0-10% children with repeated PICU admissions (n = 798), had a SMR of 100.
conclusionCompared to the matched Swedish population, SMRs were greatly elevated up to four years after PICU admission, declining from over 100 to 33 for patients with repeated PICU admissions, and from 35 to 11 for patients with a single PICU admission.
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