Evidence map›Paper›PMID 36206158›Full record

ArticleChronic respiratory disease

Diagnostic value and safety of medical thoracoscopy under local anesthesia for unexplained diffuse interstitial lung disease: A retrospective study.

Lei Zhang, Tian Xie, Yaqing Li, Bingli Zhang, Yihui Fu, Yipeng Ding, Haihong Wu

Open access · goldAbstract read
In one paragraph

Article in Chronic respiratory disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Lei ZhangDepartment of Pulmonary and Critical Care Medicine, Hainan Affiliated Hospital of Hainan Medical University, 26496Hainan General Hospital, Haikou, China.
Tian XieDepartment of Pulmonary and Critical Care Medicine, Hainan Affiliated Hospital of Hainan Medical University, 26496Hainan General Hospital, Haikou, China.
Yaqing LiDepartment of Pulmonary and Critical Care Medicine, Hainan Affiliated Hospital of Hainan Medical University, 26496Hainan General Hospital, Haikou, China.
Bingli ZhangDepartment of Pulmonary and Critical Care Medicine, Hainan Affiliated Hospital of Hainan Medical University, 26496Hainan General Hospital, Haikou, China.
Yihui FuDepartment of Pulmonary and Critical Care Medicine, Hainan Affiliated Hospital of Hainan Medical University, 26496Hainan General Hospital, Haikou, China.
Yipeng DingDepartment of Pulmonary and Critical Care Medicine, Hainan Affiliated Hospital of Hainan Medical University, 26496Hainan General Hospital, Haikou, China.
Haihong WuDepartment of Pulmonary and Critical Care Medicine, Hainan Affiliated Hospital of Hainan Medical University, 26496Hainan General Hospital, Haikou, China.ORCID 0000-0003-2975-4132
Hainan General Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveWe aimed to explore the safety and diagnostic value of medical thoracoscopic lung biopsy in patients with unexplained diffuse interstitial lung disease (ILD) in a single center pilot study.

methodWe retrospectively analyzed clinical and pathological diagnostic data from 52 patients with diffuse ILD undergoing medical thoracoscopic lung biopsy.

resultsForty-four cases of diffuse ILD were confirmed pathologically, giving a diagnostic rate of 84.6%. Among these 44 patients, 11 patients were diagnosed with cancer, including eight patients with lung adenocarcinoma, three patients with metastases; two from a gastrointestinal malignancy, and one from a granulosa cell tumor of the ovary. There were 17 cases of idiopathic interstitial pneumonia, including nine cases of usual interstitial pneumonia (UIP), four cases of non-specific interstitial pneumonia (NSIP), three cases of cryptogenic organizing pneumonia (COP), and one case of acute interstitial pneumonia (AIP). There were 12 cases of rare interstitial pneumonias, which included six cases of pulmonary alveolar proteinosis, one case each of pulmonary Langerhans cell histiocytosis (LCH) and pulmonary lymphangiomyomatosis, two cases of nodular sarcoidosis, and two cases of chronic eosinophilic pneumonia. We recorded various complications, including bleeding, infection, and pneumothorax. A total of 28 patients (53.8%) experienced at least one of the above complications, but there were no deaths associated with biopsy.

conclusionsMedical thoracoscopic lung biopsy appears a safe and effective method for diagnosing diffuse ILD of unknown cause but further prospective studies, with larger numbers, including comparison with other established techniques are required.

Indexed as

Idiopathic Interstitial PneumoniasLung Diseases, InterstitialAnesthesia, LocalBiopsyFemaleHumansLungPilot ProjectsProspective StudiesRetrospective StudiesThoracoscopyInterstitial lung diseaselocal anesthesialung biopsymedical thoracoscopypathology

Identifiers

PMID36206158
PMCPMC9549086
OpenAlexW4303501060

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.