Evidence map›Paper›PMID 36206057›Full record

ArticleJournal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research2022

Evidence for Interplay Between the Renin-Angiotensin System and Toll-Like Receptor 4 Signaling Pathways in the Induction of Virus-Induced Acute Lung Injury.

Stefanie N Vogel, Katharina Richard, Kari Ann Shirey, Fatoumata Y D Sylla, Marina S Boukhvalova, Jorge C G Blanco

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Stefanie N VogelDepartment of Microbiology and Immunology, University of Maryland, School of Medicine, Baltimore, Maryland, USA.
Katharina RichardDepartment of Microbiology and Immunology, University of Maryland, School of Medicine, Baltimore, Maryland, USA.
Kari Ann ShireyDepartment of Microbiology and Immunology, University of Maryland, School of Medicine, Baltimore, Maryland, USA.
Fatoumata Y D SyllaSigmovir Biosystems, Inc., Rockville, Maryland, USA.
Marina S BoukhvalovaSigmovir Biosystems, Inc., Rockville, Maryland, USA.
Jorge C G BlancoSigmovir Biosystems, Inc., Rockville, Maryland, USA.
Sigmovir Biosystems (United States) · USUniversity of Maryland, Baltimore · US

Funding

Eritoran (E5564), a TLR4 antagonist, as a novel therapeutic for influenzaR01AI104541 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI BLANCO, JORGE C, VOGEL, STEFANIE N. · 2013 to 2016
$3.4M
Targeting TLR Signaling Pathways to Blunt Pathogen-mediated Acute Lung InjuryR01AI125215 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI BLANCO, JORGE C, VOGEL, STEFANIE N. · 2017 to 2021
$2.7M
Macrophage differentiation and disease outcome in influenza infectionR01AI123371 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI VOGEL, STEFANIE N. · 2017 to 2021
$2.7M
NIAID NIH HHS R01 AI104541NIAID NIH HHS R01 AI123371NIAID NIH HHS R01 AI125215
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Acute Lung InjuryCOVID-19HumansMalePeptidyl-Dipeptidase ARenin-Angiotensin SystemSARS-CoV-2Signal TransductionToll-Like Receptor 4Peptidyl-Dipeptidase AToll-Like Receptor 4ACE2ALIangiotensininflammationmacrophagesRASSARS-CoV2S proteinTLR4

Identifiers

PMID36206057
PMCPMC9805881
OpenAlexW4303437998

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.