ArticleJAMA network open2022
Prevalence of Local Postoperative Complications and Breast Implant Illness in Women With Breast Implants.
Article in JAMA network open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07765953 (Thirteen-Year Trends in Primary Aesthetic Breast Augmentation, Implant Replacement, and Explantation), which is not on this map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Thirteen-Year Trends in Primary Aesthetic Breast Augmentation, Implant Replacement, and Explantation: A Prospective Observational Cohort Study
Who cites it
15 citing papers in PubMed, 27 citations in OpenAlex.
- Microbial Contamination-Mediated Inflammation Is a Major Contributor of Breast Implant Complications: Prospective Analysis of 631 Samples.Journal of clinical medicine · 2026Article
- A 20-Year Experience with Round Smooth Saline Breast Implant Explantation: Reasons, Trends, and Management.Aesthetic plastic surgery · 2026Article
- Clinical Outcomes in Women with Breast Implant Illness After Removal Surgery: Experience from a Latin American Center.Aesthetic plastic surgery · 2026Observational
- Safety of Combined Versus Isolated Cosmetic Breast Surgery and Abdominoplasty: Insights from a Multi-institutional Database.Aesthetic plastic surgery · 2025Article
- Review
- Genetic variants in the development of autoimmune complaints and capsular contracture in women with breast implants: A systematic review.JPRAS open · 2025Review
- Prevalence of Silicone Lymphadenopathy in Women with Breast Implants: A single-center retrospective study.JPRAS open · 2025Article
- Biomimetic optimization of silicone breast implant integration: insights into wound healing and the foreign body response.Frontiers in bioengineering and biotechnology · 2025Review
- Drivers and Barriers of Breast Augmentation Surgery: Multinational Insights.Aesthetic surgery journal. Open forum · 2025Article
- Medical Specialist Care Utilization Prior to the Explantation of Cosmetic Silicone Breast Implants: A Nationwide Retrospective Data Linkage Study.Aesthetic plastic surgery · 2024Article
- Breast Implants: Low Rate of Annual Check-Ups Results in Delayed Presentation of Ruptured Implants.Journal of clinical medicine · 2024Article
- Patient Satisfaction Using BREAST-Q and Breast Implant Illness after Breast Reconstruction in Transwomen.Plastic and reconstructive surgery. Global open · 2024Article
- Early Complications in Prepectoral Tissue Expander-Based Breast Reconstruction.Annals of surgical oncology · 2024Article
- Biofilm-derived oxylipin 10-HOME mediated immune response in women with breast implants.The Journal of clinical investigation · 2024Article
- A Case Report on Breast Implant Illness.Cureus · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 6 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Importance: It is unknown how often breast implant illness (BII) is the indication for revision in women with silicone breast implants. Objective: To examine how often women with silicone breast implants have their implants explanted or replaced because of BII compared with local postoperative complications. Design, Setting, and Participants: A legacy cohort study on breast implant revision surgery was conducted between April 1, 2015, and December 31, 2020, and a prospective cohort study on breast implantation and revision surgery was conducted between April 1, 2015, and December 31, 2019 (with follow-up until December 31, 2020). Data were obtained from the Dutch Breast Implant Registry. Data analysis was performed from September 2021 to August 2022. Exposures: Silicone breast implant. Main Outcomes and Measures: Breast implant revision with the indication BII or local postoperative complications. Results: All 12 882 cosmetic breast implants (6667 women; mean [SD] age, 50.6 [12.7] years) and 2945 reconstructive breast implants (2139 women, mean [SD] age, 57.9 [11.3] years) in the legacy cohort and all 47 564 cosmetic breast implants (24 120 women, mean [SD] age, 32.3 [9.7] years) and 5928 reconstructive breast implants (4688 women, mean [SD] age, 50.9 [11.5] years) in the prospective cohort were included for analysis. In the prospective cohort, 739 cosmetic breast implants (1.6%) were revised after a median (IQR) time to reoperation of 1.8 (0.9-3.1) years, and 697 reconstructive breast implants (11.8%) were revised after a median (IQR) time to reoperation of 1.1 (0.5-1.9) years. BII was registered as the reason for revision in 35 cosmetic revisions (4.7%) and 5 reconstructive revisions (0.7%) in the prospective cohort, corresponding to 0.1% of the inserted implants. In the legacy cohort, 536 cosmetic revisions (4.2%) and 80 reconstructive breast implant revisions (2.7%) were performed because of BII. Conclusions and Relevance: In this cohort study of women with silicone breast implants, BII was an uncommon indication for revision compared with local complications, both in the short and long term. In contrast to the increasing public interest in BII, these results showed that local complications are a far more common reason for breast implant revision.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.