Evidence map›Paper›PMID 36205889›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2023

Online Detection of Catecholamine Release from the Perfused Rat Adrenal Gland.

Ricardo Borges, Ana De la Iglesia, Antonio G García

Abstract read
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In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. The ex vivo perfused mouse adrenal gland-a new model to study aldosterone secretion.Pflugers Archiv : European journal of physiology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ricardo BorgesDepartment of Physical Medicine and Pharmacology, Universidad de La Laguna, La Laguna, Spain. rborges@ull.edu.es.
Ana De la IglesiaPharmacology Unit, Department of Physical Medicine and Pharmacology, Medical School, Universidad de La Laguna, Tenerife, Spain.
Antonio G GarcíaInstituto Fundación Teófilo Hernando, Departamento de Farmacología y Terapéutica, and Instituto de Investigación Sanitaria de La Princesa, Facultad de Medicina, Universidad Autónoma de Madrid, Madrid, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Retrogradely perfused adrenal glands have historically served for establishing many of our current knowledge on the stimulus-secretion coupling process. Although the use of intact adrenals has largely been switched to isolated chromaffin cells, adrenal glands are still a very valuable tool to characterize physiological and pharmacological questions. Even more, this is an excellent preparation for studying the splanchnic nerve/chromaffin cell interaction. In this chapter, we will provide the ways to (i) perform retrograde perfusion of isolated rat adrenals, (ii) the method to apply electrical splanchnic nerve stimulation, and (iii) the preparation of adrenals to conduct online electrochemical detection of catecholamine release.

Indexed as

AcetylcholineCatecholaminesAdrenal GlandsAnimalsElectric StimulationPerfusionRatsSplanchnic NervesAcetylcholineCatecholaminesCatecholamine releaseElectrochemical detectionPerfused adrenal gland

Identifiers

PMID36205889

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.