Evidence map›Paper›PMID 36205799›Full record

ArticleWiener klinische Wochenschrift2023

Bariatric surgery prevents carotid wall thickness progression.

Lukas Lunger, Andreas Melmer, Wolfgang Sturm, Claudia Lamina, Alexander Tschoner, Julia Engl, Armin Hönlinger, Clemens Engler, Peter Willeit, Stefan Kiechl and 6 more

Open access · hybridFull text read
In one paragraph

Article in Wiener klinische Wochenschrift, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 2 institutions in 3 countries.

Lukas LungerDepartment of Internal Medicine I, Gastroenterology, Hepatology & Endocrinology, Medical University of Innsbruck, Anichstr. 35, 6020, Innsbruck, Austria.
Andreas MelmerDepartment of Internal Medicine I, Gastroenterology, Hepatology & Endocrinology, Medical University of Innsbruck, Anichstr. 35, 6020, Innsbruck, Austria.
Wolfgang SturmDepartment of Internal Medicine I, Gastroenterology, Hepatology & Endocrinology, Medical University of Innsbruck, Anichstr. 35, 6020, Innsbruck, Austria.
Claudia LaminaInstitute of Genetic Epidemiology, Department of Genetics and Pharmacology, Medical University of Innsbruck, Innsbruck, Austria.
Alexander TschonerDepartment of Internal Medicine I, Gastroenterology, Hepatology & Endocrinology, Medical University of Innsbruck, Anichstr. 35, 6020, Innsbruck, Austria.
Julia EnglDepartment of Internal Medicine I, Gastroenterology, Hepatology & Endocrinology, Medical University of Innsbruck, Anichstr. 35, 6020, Innsbruck, Austria.
Armin HönlingerDepartment of Internal Medicine I, Gastroenterology, Hepatology & Endocrinology, Medical University of Innsbruck, Anichstr. 35, 6020, Innsbruck, Austria.
Clemens EnglerDepartment of Internal Medicine I, Gastroenterology, Hepatology & Endocrinology, Medical University of Innsbruck, Anichstr. 35, 6020, Innsbruck, Austria.
Peter WilleitDepartment of Neurology, Medical University of Innsbruck, Innsbruck, Austria.
Stefan KiechlDepartment of Neurology, Medical University of Innsbruck, Innsbruck, Austria.
Johann WilleitDepartment of Neurology, Medical University of Innsbruck, Innsbruck, Austria.
Dietmar ÖfnerDepartment of Visceral, Transplant and Thoracic Surgery, Centre of Operative Medicine, Medical University of Innsbruck, Innsbruck, Austria.
Heinz WykypielDepartment of Visceral, Transplant and Thoracic Surgery, Centre of Operative Medicine, Medical University of Innsbruck, Innsbruck, Austria.
Markus LaimerDepartment of Diabetes, Endocrinology, Nutritional Medicine and Metabolism, Inselspital, Bern University Hospital and University of Bern, Bern, Switzerland.
Herbert TilgDepartment of Internal Medicine I, Gastroenterology, Hepatology & Endocrinology, Medical University of Innsbruck, Anichstr. 35, 6020, Innsbruck, Austria.
Christoph EbenbichlerDepartment of Internal Medicine I, Gastroenterology, Hepatology & Endocrinology, Medical University of Innsbruck, Anichstr. 35, 6020, Innsbruck, Austria. christoph.ebenbichler@i-med.ac.at.ORCID http://orcid.org/0000-0001-5025-7929
Innsbruck Medical University · ATUniversity of Bern · CH

Funding

Austrian Science Fund KLI 348Austrian Science Fund ZFP 266730Österreichische Forschungsförderungsgesellschaft 843536
6 · The paper itself

Abstract

backgroundBariatric surgery is a treatment option for patients with severe obesity and improves parameters of cardiovascular and/or metabolic disease. Carotid intima media thickness (C-IMT) is a surrogate measure of subclinical atherosclerosis. Previous studies showed short to mid-term arrest and even regression of C‑IMT progression following bariatric surgery. We aimed to investigate the long-term effect of weight loss on C‑IMT progression 10 years after bariatric surgery in comparison to a population-based control cohort.

methodsIn total, 21 eligible patients were examined preoperatively, at 5 and 10 years after bariatric surgery. Anthropometric parameters, plasma triglycerides, total cholesterol, high-density lipoprotein cholesterol (HDL-C), insulin, and glucose were assessed at all three study visits. C‑IMT was measured via B‑mode scans of the common carotid artery. C‑IMT progression was measured in an age-matched and BMI-matched cohort selected from the population-based Bruneck study to compare with changes in C‑IMT progression after bariatric surgery.

resultsC‑IMT remained stable over the 10-year observation period after bariatric surgery. The control cohort showed a significant C‑IMT progression over 10 years. The difference in C‑IMT progression over 10 years was significant (p < 0.01) between both cohorts.

conclusionWeight loss induced by bariatric surgery halts the natural progression of C‑IMT over a 10-year observation period.

Indexed as

AtherosclerosisBariatric SurgeryCarotid Artery DiseasesCarotid Intima-Media ThicknessAdultDisease ProgressionFemaleHumansMaleMiddle AgedTreatment OutcomeWeight LossBariatric surgeryCarotid intima-media thicknessCarotid wall thickness progressionSubclinical atherosclerosisWeight loss

Identifiers

PMID36205799
PMCPMC10020246
OpenAlexW4303423355

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read29
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.