Evidence map›Paper›PMID 36205399›Full record

ArticleeLife2022

Unbiased proteomic and forward genetic screens reveal that mechanosensitive ion channel MSL10 functions at ER-plasma membrane contact sites in

Jennette M Codjoe, Ryan A Richardson, Fionn McLoughlin, Richard David Vierstra, Elizabeth S Haswell

Open access · goldAbstract read
In one paragraph

Article in eLife, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Review
  3. SUPPRESSOR OF LAZY QUADRUPLE 1 acts at ER-plasma membrane contact sites to control a gravitropism pathway in theProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  4. The Extended Synaptotagmins ofPlants (Basel, Switzerland) · 2025
    Review
  5. Article
  6. Article
  7. Studying Plant ER-PM Contact Site Localized Proteins Using Microscopy.Methods in molecular biology (Clifton, N.J.) · 2024
    Article
  8. Review
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jennette M CodjoeDepartment of Biology and the Center for Engineering Mechanobiology at Washington University in St. Louis, St. Louis, United States.ORCID 0000-0002-7766-744X
Ryan A RichardsonDepartment of Biology and the Center for Engineering Mechanobiology at Washington University in St. Louis, St. Louis, United States.
Fionn McLoughlinDepartment of Biology and the Center for Engineering Mechanobiology at Washington University in St. Louis, St. Louis, United States.
Richard David VierstraDepartment of Biology and the Center for Engineering Mechanobiology at Washington University in St. Louis, St. Louis, United States.ORCID 0000-0003-0210-3516
Elizabeth S HaswellDepartment of Biology and the Center for Engineering Mechanobiology at Washington University in St. Louis, St. Louis, United States.ORCID 0000-0002-4246-065X
Washington University in St. Louis · US

Funding

WU INSTITUTE OF CLINICAL AND TRANSLATIONAL SCIENCESUL1TR002345 · NCATS · WASHINGTON UNIVERSITY · PI William G. Powderly · 2017 to 2026
$97.8M
Washington University Institute of Clinical and Translational Sciences (UL1)UL1RR024992 · NCRR · WASHINGTON UNIVERSITY · PI EVANOFF, BRADLEY A · 2007 to 2011
$45.4M
Autophagic Clearance of Proteasomes and CDC48 as Models for Amyloidogenic Protein Quality Control.R01GM124452 · NIGMS · WASHINGTON UNIVERSITY · PI JEZ, JOSEPH MARTIN · 2018 to 2025
$2.4M
Howard Hughes Medical Institute 55108530NCATS NIH HHS UL1 TR002345NCRR NIH HHS UL1 RR024992NIGMS NIH HHS R01 GM124452
6 · The paper itself

Abstract

Mechanosensitive (MS) ion channels are an evolutionarily conserved way for cells to sense mechanical forces and transduce them into ionic signals. The channel properties of

Indexed as

ArabidopsisArabidopsis ProteinsCell MembraneIon ChannelsMembrane ProteinsProteomicsArabidopsis ProteinsIon ChannelsMembrane ProteinsMSL10 protein, ArabidopsisA. thalianamechanosensitive ion channelmechanotransductionmembrane contact sitesplant biologysynaptotagminsVAMP-associated proteins

Identifiers

PMID36205399
PMCPMC9625087
OpenAlexW4303423723

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.