Evidence map›Paper›PMID 36205393›Full record

ArticleeLife2022

Distinct neurexin-cerebellin complexes control AMPA- and NMDA-receptor responses in a circuit-dependent manner.

Jinye Dai, Kif Liakath-Ali, Samantha Rose Golf, Thomas C Südhof

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in eLife, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Article
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  4. Glutamate Delta 1 Receptor in Synapses, Circuits, and Disease.The European journal of neuroscience · 2026
    Review
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  10. Review
  11. Article
  12. Dorsal raphe dopaminergic neurons target CaMKIITranslational psychiatry · 2024
    Article
  13. Article
  14. Review
  15. Postsynaptic receptors regulate presynaptic transmitter stability through transsynaptic bridges.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  16. Presynaptic Nrxn3 is essential for ribbon-synapse assembly in hair cells.bioRxiv : the preprint server for biology · 2024
    Article
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Jinye DaiHoward Hughes Medical Institute, Stanford University, Stanford, United States.ORCID https://orcid.org/0000-0002-8497-3154
Kif Liakath-AliDepartment of Molecular and Cellular Physiology, Stanford University, Stanford, United States.ORCID https://orcid.org/0000-0001-9047-7424
Samantha Rose GolfDepartment of Molecular and Cellular Physiology, Stanford University, Stanford, United States.
Thomas C SüdhofHoward Hughes Medical Institute, Stanford University, Stanford, United States.ORCID https://orcid.org/0000-0003-3361-9275
Howard Hughes Medical Institute · USStanford University · US

Funding

Training Program in Basic NeuroscienceT32MH020016 · NIMH · STANFORD UNIVERSITY · PI Justin L Gardner, Merritt C Maduke · 1997 to 2026
$16.2M
FUNCTION OF NEUREXINSR37MH052804 · NIMH · UT SOUTHWESTERN MEDICAL CENTER · PI SUDHOF, THOMAS C. · 2000 to 2019
$9.3M
Function of NeurexinsR01MH052804 · NIMH · UNIVERSITY OF TEXAS SW MED CTR/DALLAS · PI SUDHOF, THOMAS C. · 1994 to 2024
$3.7M
NIMH NIH HHS R01 MH052804NIMH NIH HHS R37 MH052804NIMH NIH HHS T32 MH020016
6 · The paper itself

Abstract

At CA1→subiculum synapses, alternatively spliced neurexin-1 (Nrxn1

Indexed as

Calcium-Binding ProteinsNeural Cell Adhesion MoleculesReceptors, AMPAReceptors, N-Methyl-D-Aspartatealpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic AcidAnimalsMiceNerve Tissue ProteinsN-MethylaspartateProtein PrecursorsSynapsesalpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic AcidCalcium-Binding ProteinscerebellinNerve Tissue ProteinsNeural Cell Adhesion Moleculesneurexin 3, mouseN-MethylaspartateNrxn1 protein, mouseProtein PrecursorsReceptors, AMPAReceptors, N-Methyl-D-Aspartatecell biologycerebellinscerebellumhippocampusmouseneurexin signaling specificityneuroscienceprefrontal cortexsynaptic transmission

Identifiers

PMID36205393
PMCPMC9586558
OpenAlexW4303423649

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.