Evidence map›Paper›PMID 36205386›Full record

ArticleEarly intervention in psychiatry2023

Investigating temporal and prosodic markers in clinical high-risk for psychosis participants using automated acoustic analysis.

Bianca Bianciardi, Ruchika Gajwani, Joachim Gross, Andrew I Gumley, Stephen M Lawrie, Melina Moelling, Matthias Schwannauer, Frauke Schultze-Lutter, Alessio Fracasso, Peter J Uhlhaas

Open access · hybridAbstract read
In one paragraph

Article in Early intervention in psychiatry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 4 countries.

Bianca BianciardiInstitute of Neuroscience and Psychology, University of Glasgow, Glasgow, UK.ORCID 0000-0003-0841-4542
Ruchika GajwaniSchool of Health and Wellbeing, University of Glasgow, Glasgow, UK.ORCID 0000-0002-1199-320X
Joachim GrossInstitute for Biomagnetism and Biosignalanalysis, University of Muenster, Muenster, Germany.
Andrew I GumleySchool of Health and Wellbeing, University of Glasgow, Glasgow, UK.
Stephen M LawrieDepartment of Psychiatry, Univ. of Edinburgh, Edinburgh, UK.
Melina MoellingInstitute of Neuroscience and Psychology, University of Glasgow, Glasgow, UK.
Matthias SchwannauerDepartment of Clinical Psychology, Univ. of Edinburgh, Edinburgh, UK.
Frauke Schultze-LutterDepartment of Psychiatry and Psychotherapy, Medical Faculty, Heinrich Heine University, Düsseldorf, Germany.ORCID 0000-0003-1956-9574
Alessio FracassoInstitute of Neuroscience and Psychology, University of Glasgow, Glasgow, UK.
Peter J UhlhaasInstitute of Neuroscience and Psychology, University of Glasgow, Glasgow, UK.ORCID 0000-0002-0892-2224
University of Glasgow · GBUniversity of Edinburgh · GBCharité - Universitätsmedizin Berlin · DEUniversity of Bern · CHUniversity of Münster · DE

Funding

Biotechnology and Biological Sciences Research Council BBS00/6605/1Medical Research Council L011689Medical Research Council MR/L011689/1
6 · The paper itself

Abstract

aimLanguage disturbances are a candidate biomarker for the early detection of psychosis. Temporal and prosodic abnormalities have been observed in schizophrenia patients, while there is conflicting evidence whether such deficits are present in participants meeting clinical high-risk for psychosis (CHR-P) criteria.

methodsClinical interviews from CHR-P participants (n = 50) were examined for temporal and prosodic metrics and compared against a group of healthy controls (n = 17) and participants with affective disorders and substance abuse (n = 23).

resultsThere were no deficits in acoustic variables in the CHR-P group, while participants with affective disorders/substance abuse were characterized by slower speech rate, longer pauses and higher unvoiced frames percentage.

conclusionOur finding suggests that temporal and prosodic aspects of speech are not impaired in early-stage psychosis. Further studies are required to clarify whether such abnormalities are present in sub-groups of CHR-P participants with elevated psychosis-risk.

Indexed as

Psychotic DisordersSchizophreniaAcousticsEarly DiagnosisHumansMood Disordersautomated acoustic analysisclinical high-riskearly psychosisprosodyspeech

Identifiers

PMID36205386
PMCPMC10946925
OpenAlexW4303418729

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.