ReviewJournal of the American Heart Association2022
Therapeutic Management of Anomalous Coronary Arteries Originating From the Opposite Sinus of Valsalva: Current Evidence, Proposed Approach, and the Unknowing.
Review in Journal of the American Heart Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06089902 (EUROAAOCA Registry), which is not on this map. Cited by 57 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
EUROAAOCA Registry
Who cites it
57 citing papers in PubMed, 1 synthesis or guideline pooled it, 73 citations in OpenAlex.
- Cardiac evaluation of paediatric athletes.European heart journal · 2026Guideline
- Single Coronary Artery in the Context of Vascular Disease: Anatomy, Development, Multimodality Imaging, and Clinical Interpretation.Journal of clinical medicine · 2026Review
- Chest Pain Due to Anomalous Origin of the Left Circumflex Artery From the Opposite Sinus of Valsalva in a 70-Year-Old Woman.The American journal of case reports · 2026Article
- Covered Stent Correction of Sinus Venosus ASD With Anomalous Left Sinus Interarterial Right Coronary Artery.JACC. Case reports · 2026Article
- Patient-specific hemodynamic assessment using experimental and computational approaches in anomalous aortic origin of the coronary artery: Case study.JTCVS techniques · 2026Article
- Coronary Artery Anomalies Revisited: Description of the Types, Pathophysiology and Treatment Options Based on Latest Guidelines.Journal of clinical medicine · 2026Review
- Innovative catheter modification for engaging an anomalous right coronary artery: a case report.European heart journal. Case reports · 2026Article
- High-takeoff anomalous right coronary artery arising from the ascending aorta: a case report.BMC cardiovascular disorders · 2026Article
- One origin, diverse courses: coronary CTA evaluation of single coronary artery variants from the right sinus of Valsalva.The international journal of cardiovascular imaging · 2026Article
- Coronary Artery Origin Anomalies on Coronary CT Angiography: A Single-Center Tertiary-Care Cohort.Journal of clinical practice and research · 2026Article
- Coronary artery anomalies in children: subtype classification, age of onset, clinical outcomes, and prognostic implications.BMC pediatrics · 2026Article
- Computed tomography-derived biomechanical simulations as a proof-of-concept tool for evaluating coronary dynamics in anomalous aortic origin of coronary arteries.European heart journal. Digital health · 2026Article
- Optical coherence tomography in an anomalous left circumflex coronary artery with stent thrombosis due to extrinsic compression in hereditary hemorrhagic telangiectasia: a case report.Journal of visualized surgery · 2026Article
- [Anomalous origin of the left anterior descending artery from the right coronary artery: A case report].Revista medica del Instituto Mexicano del Seguro Social · 2026Article
- Case Report: Syncope in an 11-year-old girl induced by anomalous aortic origin of the coronary artery, initially diagnosed via echocardiography.Frontiers in cardiovascular medicine · 2026Article
- Myocardial Ischemia Secondary to Anomalous Origin of Left Anterior Descending Coronary Artery: A Case Report and Literature Review.The American journal of case reports · 2025Review
- CT-Derived Fractional Flow Reserve Guides Surgical Revascularization in Anomalous Long Left Anterior Descending With Curly-Q Intramyocardial Course.JACC. Case reports · 2025Article
- Clinical features and prognosis in patients with coronary anomalies: the experiences and follow-up results of a single center.Postepy w kardiologii interwencyjnej = Advances in interventional cardiology · 2025Article
- Survival After Cardiac Arrest Due to an Anomalous Right Coronary Artery in a Young Athlete.JACC. Case reports · 2025Article
- "Single Coronary Artery" from Right Sinus-Uncommon Causes of Ischemia with Non-Obstructive Coronary Arteries.Diagnostics (Basel, Switzerland) · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Anomalous coronary arteries originating from the opposite sinus of Valsalva (ACAOS) are a challenge because of their various anatomic and clinical presentation. Although the prevalence is low, the absolute numbers of detected ACAOS are increasing because of the growing use of noninvasive anatomical imaging for ruling out coronary artery disease. As evidence-based guidelines are lacking, treating physicians are left in uncertainty for the optimal management of such patients. The sole presence of ACAOS does not justify surgical correction, and therefore a thorough anatomic and hemodynamic assessment is warranted. Invasive and noninvasive multimodality imaging provides information to the clinical question whether the presence of ACAOS is an innocent coincidental finding, is responsible for the patient's symptoms, or even might be a risk for sudden cardiac death. Based on recent clinical data, focusing on the pathophysiology of patients with ACAOS, myocardial ischemia is dependent on both the extent of fixed and dynamic components, represented by anatomic high-risk features. These varying combinations should be considered individually in the decision making for the different therapeutic options. This state-of-the-art review focuses on the advantages and limitations of the common contemporary surgical, interventional, and medical therapy with regard to the anatomy and pathophysiology of ACAOS. Further, we propose a therapeutic management algorithm based on current evidence on multimodality invasive and noninvasive imaging findings and highlight remaining gaps of knowledge.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.