Evidence map›Paper›PMID 36205191›Full record

ArticleLab on a chip2022

Tissue clearing of human iPSC-derived organ-chips enables high resolution imaging and analysis.

Briana N Ondatje, Samuel Sances, Michael J Workman, Clive N Svendsen

Abstract read
In one paragraph

Article in Lab on a chip, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Briana N OndatjeCedars-Sinai Board of Governors Regenerative Medicine Institute, Los Angeles, CA, USA. clive.svendsen@cshs.org.ORCID 0000-0002-1992-2625
Samuel SancesCedars-Sinai Board of Governors Regenerative Medicine Institute, Los Angeles, CA, USA. clive.svendsen@cshs.org.
Michael J WorkmanCedars-Sinai Board of Governors Regenerative Medicine Institute, Los Angeles, CA, USA. clive.svendsen@cshs.org.
Clive N SvendsenCedars-Sinai Board of Governors Regenerative Medicine Institute, Los Angeles, CA, USA. clive.svendsen@cshs.org.ORCID 0000-0001-8696-3446

Funding

Effects of opioids on reward systems in organ chipsUG3NS105703 · NINDS · CEDARS-SINAI MEDICAL CENTER · PI SVENDSEN, CLIVE NIELS · 2017 to 2020
$5.2M
A microphysiologic multicellular organ-on-chip to inform clinical trials in FTD/ALSUG3TR003264 · NCATS · CEDARS-SINAI MEDICAL CENTER · PI SVENDSEN, CLIVE NIELS · 2020 to 2021
$1.6M
NCATS NIH HHS UG3 TR003264NINDS NIH HHS UG3 NS105703
6 · The paper itself

Abstract

Engineered microfluidic organ-chips enable increased cellular diversity and function of human stem cell-derived tissues grown

Indexed as

Induced Pluripotent Stem CellsDimethylpolysiloxanesHumansImaging, Three-DimensionalMicrofluidicsDimethylpolysiloxanes

Identifiers

PMID36205191
PMCPMC9595176

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.