Evidence map›Paper›PMID 36205130›Full record

ArticleJournal of cutaneous medicine and surgery

Dental Screening Including Panoramic Radiograph for Gorlin-Goltz Syndrome in Patients With Multiple Basal Cell Carcinomas.

Poramate Pitak-Arnnop, Levyn Kay Witohendro, Chatpong Tangmanee, Anonknart Bhakdinaronk, Keskanya Subbalekha, Prim Auychai, Nattapong Sirintawat, Jean-Paul Meningaud, Andreas Neff

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of cutaneous medicine and surgery. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 57% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 3 countries.

Poramate Pitak-Arnnop61061 Faculty of Medicine, Philipps-University of Marburg, and Department of Oral and Craniomaxillofacial Plastic Surgery, UKGM GmbH, University Hospital Marburg, Marburg, Germany.ORCID 0000-0002-7427-3461
Levyn Kay Witohendro144867 Faculty of Medicine, Goethe University, Frankfurt am Main, Germany.
Chatpong Tangmanee67950 Department of Statistics, Chulalongkorn Business School, Chulalongkorn University, Bangkok, Thailand.
Anonknart Bhakdinaronk90449 Division of Oral and Maxillofacial Radiology, Department of Oral Diagnosis, Faculty of Dentistry, Naresuan University Phitsanulok, Phitsanulok, Thailand.
Keskanya Subbalekha54773 Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Chulalongkorn University, Bangkok, Thailand.
Prim Auychai54773 Department of Pediatric Dentistry, Faculty of Dentistry, Chulalongkorn University, Bangkok, Thailand.
Nattapong Sirintawat67975 Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Mahidol University, Bangkok, Thailand.
Jean-Paul Meningaud432204 Department of Plastic, Reconstructive, Esthetic and Maxillofacial Surgery, Henri Mondor University Hospital, AP-HP, Faculty of Medicine, University Paris-Est Créteil Val de Marne (Paris XII), Créteil, France.
Andreas Neff61061 Faculty of Medicine, Philipps-University of Marburg, and Department of Oral and Craniomaxillofacial Plastic Surgery, UKGM GmbH, University Hospital Marburg, Marburg, Germany.
Chulalongkorn University · THPhilipps University of Marburg · DEGoethe University Frankfurt · DEMahidol University · THNaresuan University · THUniversité Paris-Est Créteil · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo answer the following clinical research question: "Among patients with multiple basal cell carcinomas (mBCCs), can panoramic radiograph (PaR) facilitate the diagnosis of Gorlin-Goltz syndrome (GGS)?"

methodsThis retrospective study enrolled mBCCs subjects who presented to a German tertiary care center between 1 January 2015 and 31 December 2021. The primary predictor was presence of syndromic mBCCs, and the main outcomes were jaw cysts and odontogenic keratocysts (OKCs). Descriptive, bi- and multivariate statistics, diagnostic test evaluation, and number needed to screen (NNS) were computed at α = 95%.

resultsThe sample comprised 527 mBCCs patients (36.1% females; 6.8% GGS; 5.5% OKCs; mean age, 74.5 ± 15.8 years [range, 15-102]). There was a significant association between syndromic mBCCs and jaw cysts (

conclusionsDental screening with the use of PaR for mBCCs patients, especially those aged ≤35 years, or with ≥5 BCCs, or ≥1 high-risk BCCs, may be helpful in detection and identification of GGS through recognition of OKCs.

Indexed as

Basal Cell CarcinomaBasal Cell Nevus SyndromeOdontogenic CystsAgedAged, 80 and overFemaleHamartoma Syndrome, MultipleHumansMaleMiddle AgedRadiography, PanoramicRetrospective Studiesbasal cell carcinomaGorlin-Goltz syndromeodontogenic keratocystpanoramic radiographscreening

Identifiers

PMID36205130
PMCPMC9729970
OpenAlexW4303515393

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.