Evidence map›Paper›PMID 36204798›Full record

ReviewEndoscopic ultrasound

EUS-guided

Saurabh Chandan, Smit Deliwala, Shahab R Khan, Babu P Mohan, Banreet S Dhindsa, Jay Bapaye, Hemant Goyal, Lena L Kassab, Faisal Kamal, Harlan R Sayles and 2 more

2 registry-linked trialsOpen access · hybridAbstract readReview
In one paragraph

Review in Endoscopic ultrasound. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06231082 naunknown statusnot on this map

Bloody or Well Done. How Would You Like Your Liver Biopsy, Sir? Post Liver bIopsy abdoMinal PaIn as Predictive Factor for Liver bleeDing (LIMPID)

TypeinterventionalSponsorCarol Davila University of Medicine and PharmacyRan2024 to 2024Enrolled78ConditionsLiver Disease ParenchymalArmsGroup one - percutaneous (P), Group two - EUS FNB (E)
NCT07701031 completednot on this map

Assessing EUS and Percutaneous Untargeted Liver Biopsy Quality: A Sequential-Period Cluster-Randomized Study

TypeobservationalSponsorUniversity Hospital MuensterRan2023 to 2024Enrolled146ConditionsLiver Cirrhosis, Liver Disease Chronic, Liver TransplantArmsEUS Liver biopsy 19G FNA, EUS LB 19G FNB, EUS LB 22G FNB, EUS LB 22G FNA, PC-LB 18G Trucut
3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 41 citations in OpenAlex.

  1. Trial
  2. Review
  3. Review
  4. Review
  5. Endoscopic ultrasound-guided liver biopsy: Are we ready for routine use?World journal of gastrointestinal endoscopy · 2026
    Article
  6. Review
  7. Review
  8. Review
  9. Article
  10. Pediatric endoscopic ultrasound-guided liver biopsy: 3-year experience.Journal of pediatric gastroenterology and nutrition · 2025
    Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Review
  17. Article
  18. Article
  19. EUS-guidedEndoscopic ultrasound
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 10 institutions in 1 country.

Saurabh ChandanDivision of Gastroenterology and Hepatology, CHI Creighton University Medical Center, Omaha, Nebraska, USA.
Smit DeliwalaDepartment of Internal Medicine, Hurley Medical Center, Flint, Michigan, USA.
Shahab R KhanDepartment of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Babu P MohanDivision of Gastroenterology and Hepatology, University of Utah School of Medicine, Salt Lake City, Utah, USA.
Banreet S DhindsaDivision of Gastroenterology and Hepatology, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Jay BapayeDepartment of Internal Medicine, Rochester General Hospital, Rochester, New York, USA.
Hemant GoyalDepartment of Gastroenterology, The Wright Center for Graduate Medical Education, Scranton, Pennsylvania, USA.
Lena L KassabDepartment of Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA.
Faisal KamalDivision of Gastroenterology, University of California-San Francisco, California, USA.
Harlan R SaylesDepartment of Biostatistics, College of Public Health, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Gursimran S KochharDivision of Gastroenterology, Hepatology and Nutrition, Allegheny Health Network, Pittsburgh, Pennsylvania, USA.
Douglas G AdlerCenter for Advanced Therapeutic Endoscopy, Centura Health, Porter Adventist Hospital, Denver, Colorado, USA.
Hurley Medical Center · USUniversity of Nebraska Medical Center · USAllegheny Health Network · USCHI Health Creighton University Medical Center - Bergan Mercy · USHarvard University · USMayo Clinic · USRochester General Hospital · USThe Wright Center for Graduate Medical Education · USUniversity of California, San Francisco · USUniversity of Utah · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

EUS-guided liver biopsy (EUS-LB) has gained momentum in recent years, especially with availability of newer needle designs. Given the emerging comparative data on EUS-LB with second-generation needles and percutaneous LB (PC-LB), we conducted a systematic review and meta-analysis to compare the safety and efficacy of the two techniques. We searched multiple databases from inception through November 2021 to identify studies comparing outcomes of EUS-LB and PC-LB. Pooled estimates were calculated using a random-effects model, and the results were expressed in terms of pooled proportions and odds ratio (OR) along with relevant 95% confidence intervals (CIs). Five studies with 748 patients were included in the final analysis. EUS-LB was performed in 276 patients and PC-LB in 472 patients. Across all studies, PC-LB had an overall higher diagnostic accuracy than EUS-LB, 98.6% confidence interval (CI: 94.7-99.7) versus 88.3% (49.6-98.3), OR: 1.65, P = 0.04. On assessing data from randomized controlled trials, there was no difference between the two. While pooled diagnostic adequacy and overall adverse events were not significantly different between PC-LB and EUS-LB, the former was superior in terms of the mean number of complete portal tracts (CPT) and total specimen length. PC-LB and EUS-LB produce similar results. PC-LB allows obtaining longer samples and more CPT. Further studies are needed to see if these trends hold up as more providers begin to perform EUS-LB.

Indexed as

EUSliver biopsymeta-analysis

Identifiers

PMID36204798
PMCPMC10237604
OpenAlexW4303516058

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.