Evidence map›Paper›PMID 36204787›Full record

ArticleMedical gas research

Inhalation of 4% and 67% hydrogen ameliorates oxidative stress, inflammation, apoptosis, and necroptosis in a rat model of glycerol-induced acute kidney injury.

Jun-Li Xue, Bo-Yan Liu, Min Zhao, Meng-Yu Zhang, Ming-Yue Wang, Qian-Qian Gu, Xiao-Yi Zhang, Shu-Cun Qin

Open access · hybridAbstract read
In one paragraph

Article in Medical gas research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Jun-Li XueThe Second Affiliated Hospital of Shandong First Medical University; College of Basic Medical Sciences in Shandong First Medical University & Shandong Academy of Medical Sciences; Taishan Institute for Hydrogen Biomedicine, Shandong First Medical University & Shandong Academy of Medical Sciences, Taian, Shandong Province, China.
Bo-Yan LiuThe Second Affiliated Hospital of Shandong First Medical University; College of Basic Medical Sciences in Shandong First Medical University & Shandong Academy of Medical Sciences; Taishan Institute for Hydrogen Biomedicine, Shandong First Medical University & Shandong Academy of Medical Sciences, Taian, Shandong Province, China.
Min ZhaoTaishan Institute for Hydrogen Biomedicine, Shandong First Medical University & Shandong Academy of Medical Sciences, Taian, Shandong Province, China.
Meng-Yu ZhangTaishan Institute for Hydrogen Biomedicine, Shandong First Medical University & Shandong Academy of Medical Sciences, Taian, Shandong Province, China.
Ming-Yue WangTaishan Institute for Hydrogen Biomedicine, Shandong First Medical University & Shandong Academy of Medical Sciences, Taian, Shandong Province, China.
Qian-Qian GuTaishan Institute for Hydrogen Biomedicine, Shandong First Medical University & Shandong Academy of Medical Sciences, Taian, Shandong Province, China.
Xiao-Yi ZhangTaishan Institute for Hydrogen Biomedicine, Shandong First Medical University & Shandong Academy of Medical Sciences, Taian, Shandong Province, China.
Shu-Cun QinThe Second Affiliated Hospital of Shandong First Medical University; Taishan Institute for Hydrogen Biomedicine, Shandong First Medical University & Shandong Academy of Medical Sciences, Taian, Shandong Province, China.
Shandong First Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute kidney injury (AKI) is the major complication of rhabdomyolysis (RM) clinically, which is usually mimicked by glycerol injection in basic research. Oxidative stress, inflammatory response and apoptosis are recognized to play important roles in development of this disease. Recently, numerous studies have reported the therapeutic effects of molecular hydrogen (H

Indexed as

Acute Kidney InjuryRhabdomyolysisAnimalsAnti-Inflammatory AgentsAntioxidantsApoptosisBiomarkersGlycerolHydrogenInflammationNecroptosisOxidative StressRatsAnti-Inflammatory AgentsAntioxidantsBiomarkersGlycerolHydrogenacute kidney injuryapoptosisglycerolhydrogen gasinflammationnecroptosisoxidative stressrats

Identifiers

PMID36204787
PMCPMC9555022
OpenAlexW4285109245

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.