Evidence map›Paper›PMID 36204642›Full record

ArticleFrontiers in cellular and infection microbiology2022

Comprehensive analysis of a TPX2-related TRHDE-AS1/PKIA ceRNA network involving prognostic signatures in Hepatitis B virus-infected hepatocellular carcinoma.

Gaopeng Li, Zhuangqiang Wang, Dong Chen, Jun Yin, Zhiyuan Mo, Bianyin Sun, Tao Yang, Xinning Zhang, Zhensheng Zhai, Yaoxuan Li and 4 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Translational cancer research · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Gaopeng LiGeneral Surgery Department, Shanxi Bethune Hospital, Taiyuan, China.
Zhuangqiang WangGeneral Surgery Department, Shanxi Bethune Hospital, Taiyuan, China.
Dong ChenGeneral Surgery Department, Shanxi Bethune Hospital, Taiyuan, China.
Jun YinGeneral Surgery Department, Shanxi Bethune Hospital, Taiyuan, China.
Zhiyuan MoGeneral Surgery Department, Shanxi Bethune Hospital, Taiyuan, China.
Bianyin SunGeneral Surgery Department, Shanxi Bethune Hospital, Taiyuan, China.
Tao YangGeneral Surgery Department, Shanxi Bethune Hospital, Taiyuan, China.
Xinning ZhangGeneral Surgery Department, Shanxi Bethune Hospital, Taiyuan, China.
Zhensheng ZhaiGeneral Surgery Department, Shanxi Bethune Hospital, Taiyuan, China.
Yaoxuan LiGeneral Surgery Department, Shanxi Bethune Hospital, Taiyuan, China.
Pinggui ChenGeneral Surgery Department, Shanxi Bethune Hospital, Taiyuan, China.
Yunyan DaiGeneral Surgery Department, Shanxi Bethune Hospital, Taiyuan, China.
Zhiming WangGeneral Surgery Department, Shanxi Bethune Hospital, Taiyuan, China.
Jun MaGeneral Surgery Department, Shanxi Bethune Hospital, Taiyuan, China.
Shanxi Academy of Medical Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatitis B virus (HBV) infection is a main carcinogenic factor of hepatocellular carcinoma (HCC). TPX2 microtubule nucleation factor is recently recommended as a novel prognostic biomarker in HBV-infected HCC tissues. This study aimed to explore a TPX2-related ceRNA regulatory network in HBV-infected HCC and the potential impact on HCC prognosis. We comprehensively identified 541 differential expressed lncRNAs (DElncRNAs), 37 DEmiRNAs and 439 DEmRNAs from HBV-related TCGA-HCC cohorts in TPX2

Indexed as

Carcinoma, HepatocellularLiver NeoplasmsMicroRNAsRNA, Long NoncodingBiomarkersCell Cycle ProteinsGene Expression Regulation, NeoplasticGene Regulatory NetworksHepatitis B virusHumansIntracellular Signaling Peptides and ProteinsKinesinsMicrotubule-Associated ProteinsPrognosisRNA, MessengerShc Signaling Adaptor ProteinsBiomarkersCell Cycle ProteinsIntracellular Signaling Peptides and ProteinsKIF18A protein, humanKinesinsMicroRNAsMicrotubule-Associated ProteinsRNA, Long NoncodingRNA, MessengerSHCBP1 protein, humanShc Signaling Adaptor ProteinsTPX2 protein, humanceRNAhepatitis B virushepatocellular carcinomaimmune infiltrationprognosis

Identifiers

PMID36204642
PMCPMC9530265
OpenAlexW4296389222

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.