Evidence map›Paper›PMID 36204460›Full record

ArticleJournal of cellular signaling2022

Oxidative DNA Damage: A Role in Altering Neuronal Function.

Adib Behrouzi, Mark R Kelley, Jill C Fehrenbacher

Open access · hybridAbstract read
In one paragraph

Article in Journal of cellular signaling, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 13 citations in OpenAlex.

  1. Origins and timing of somatic variants in the brain.Current opinion in genetics & development · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Adib BehrouziDepartment of Pharmacology and Toxicology, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
Mark R KelleyDepartment of Pharmacology and Toxicology, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
Jill C FehrenbacherDepartment of Pharmacology and Toxicology, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
Indiana University School of MedicineIndiana University Health · US

Funding

(PQ9)Mechanistic Role of APE1 and BER in chemotherapy-induced peripheral neuropathyR01CA205166 · NCI · INDIANA UNIVERSITY INDIANAPOLIS · PI FEHRENBACHER, JILL C, KELLEY, MARK R. · 2017 to 2021
$2.7M
(PQ12) Enhancement of DNA repair in neurons via a targeted APE1 small molecule modifier to decrease and reverse chemotherapy-induced peripheral neuropathy (CIPN)R01CA231267 · NCI · INDIANA UNIVERSITY INDIANAPOLIS · PI FEHRENBACHER, JILL C, KELLEY, MARK R. · 2018 to 2022
$2.3M
NCI NIH HHS R01 CA205166NCI NIH HHS R01 CA231267
6 · The paper itself

Abstract

A role for oxidative stress in the etiology of myriad neuropathologies is well accepted. However, the specific effects of oxidative DNA damage in the onset or promotion of neuronal dysfunction have been less studied. In our recent publication by Behrouzi

Indexed as

8-oxoguanine DNA glycosylase-1AgingAlzheimer’s diseaseAmyotrophic lateral sclerosisApurinic/apyrimidinic endonuclease/redox effector factor 1Base excision repairChemotherapy-induced peripheral neuropathyInflammatory bowel diseaseOxidative DNA damageOxidative stress

Identifiers

PMID36204460
PMCPMC9534318
OpenAlexW4297884013

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.