ArticleFrontiers in surgery2022
Cerebrospinal fluid leaks following intradural spinal surgery-Risk factors and clinical management.
Article in Frontiers in surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.
- Effect of intradural decompression on neurological recovery in acute spinal cord injury: a systematic review and meta-analysis.Spinal cord · 2026Pooled it
- Drain versus no drain after intradural spine surgery: a 10-year multicenter study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Multidisciplinary Approach in Management of Currarino Syndrome in a Female Infant: A Case Report on Rare Congenital Triad and Focused Literature Review.Clinical case reports · 2026Article
- Risk factors for cerebrospinal fluid leakage after spinal tumor surgery: a systematic review and meta-analysis.Translational cancer research · 2026Article
- Delayed myelopathy caused by cerebrospinal fluid pseudocyst following decompression for thoracic ossification of the ligamentum flavum: a case report and literature review.BMC musculoskeletal disorders · 2026Review
- Fibrin glue-coated collagen matrix is superior to fibrin glue-coated polyglycolic acid for preventing cerebral spinal fluid leakage after spinal durotomy.Scientific reports · 2024Article
- Does Early Mobilization Following Resection of Spinal Intra-Dural Pathology Increase the Risk of Cerebrospinal Fluid Leaks?-A Dual-Center Comparative Effectiveness Research.Medicina (Kaunas, Lithuania) · 2024Article
- Subfascial drains are safe and effective in preventing postoperative cerebrospinal fluid leaks after intradural spine tumor surgery.Surgical neurology international · 2024Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Cerebrospinal fluid leakage (CSFL) following spinal durotomy can lead to severe sequelae. However, while several studies have investigated accidental spinal durotomies, the risk factors and influence of clinical management in planned durotomies remain unclear. Methods: We performed a retrospective analysis of all patients who underwent planned intradural spinal surgery at our institution between 2010 and 2020. Depending on the occurrence of a CSFL, patients were dichotomized and compared with respect to patient and case-related variables as well as dural closure technique, epidural drainage placement, and timing of mobilization. Results: A total of 351 patients were included. CSFL occurred in 4.8% of all cases. Surgical indication, tumor histology, location within the spine, previous intradural surgery, and medical comorbidities were not associated with an increased risk of CSFL development (all Conclusion: CSFL following planned durotomy pose a relevant and quantifiable complication risk of surgery that should be factored in during preoperative patient counseling. Our data could not demonstrate superiority of any particular dural closure technique but support the safety of both early mobilization within 24 h postoperatively and epidural drainage with reduced or no force of suction.
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