Evidence map›Paper›PMID 36204332›Full record

ArticleSynthetic and systems biotechnology2022

Translocation of subunit PPSE in plipastatin synthase and synthesis of novel lipopeptides.

Ling Gao, Wenjie Ma, Zhaoxin Lu, Jinzhi Han, Zhi Ma, Hongxia Liu, Xiaomei Bie

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Synthetic and systems biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Ling GaoNanjing Agricultural University, College of Food Science and Technology, Nanjing, 210095, China.
Wenjie MaNanjing Agricultural University, College of Food Science and Technology, Nanjing, 210095, China.
Zhaoxin LuNanjing Agricultural University, College of Food Science and Technology, Nanjing, 210095, China.
Jinzhi HanNanjing Agricultural University, College of Food Science and Technology, Nanjing, 210095, China.
Zhi MaNanjing Agricultural University, College of Food Science and Technology, Nanjing, 210095, China.
Hongxia LiuNanjing Agricultural University, College of Food Science and Technology, Nanjing, 210095, China.
Xiaomei BieNanjing Agricultural University, College of Food Science and Technology, Nanjing, 210095, China.
Nanjing Agricultural University · CNJiangnan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nonribosomal peptide synthase (NRPS) is a unique molecular assembly mechanism with high hybridity. Its recombination is conducive to the development of novel lipopeptides. However, there are few reports on NRPS subunit recombination of plipastatin at present. In this paper, plipastatin synthase was modified by the forward movement of subunit PPSE and the replacement of the communication-mediating (COM) domain. The results showed that ppsABE, a new assembly line, could synthesize novel lipopeptides such as cycle pentapeptide (C

Indexed as

Antimicrobial activityCOM domainCompatibilityNovel lipopeptidesPlipastatinSubunit translocation

Identifiers

PMID36204332
PMCPMC9519435
OpenAlexW4296444864

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.