Evidence map›Paper›PMID 36204262›Full record

SynthesisCanadian journal of gastroenterology & hepatology2022

Neutrophil to Lymphocyte Ratio and Spontaneous Bacterial Peritonitis among Cirrhotic Patients: A Systematic Review and Meta-analysis.

Seyed Arsalan Seyedi, Seyed Ali Nabipoorashrafi, Jairo Hernandez, Andrew Nguyen, Brandon Lucke-Wold, Shima Nourigheimasi, Shokoufeh Khanzadeh

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Canadian journal of gastroenterology & hepatology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  8. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Seyed Arsalan SeyediEndocrinology and Metabolism Research Center (EMRC), Vali-Asr Hospital, School of Medicine, Tehran, Iran.
Seyed Ali NabipoorashrafiEndocrinology and Metabolism Research Center (EMRC), Vali-Asr Hospital, School of Medicine, Tehran, Iran.
Jairo HernandezDepartment of Neurosurgery, University of Florida, Gainesville, USA.
Andrew NguyenDepartment of Neurosurgery, University of Florida, Gainesville, USA.
Brandon Lucke-WoldDepartment of Neurosurgery, University of Florida, Gainesville, USA.
Shima NourigheimasiSchool of Medicine, Arak University of Medical Sciences, Arak, Iran.
Shokoufeh KhanzadehStudent Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran.ORCID 0000-0002-4177-8746

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The goal of this systematic review and meta-analysis was analyzing published studies on the role of neutrophil to lymphocyte ratio (NLR) in infection and spatially spontaneous bacterial peritonitis (SBP) among cirrhotic patients. Methods: PubMed, Web of Science, and Scopus were searched until May 24, 2022. The Newcastle-Ottawa scale was used for quality assessment. Results: Of 14 studies included in our study, six studies were on infection with 2786 hospitalized cirrhotic patients, of whom 934 developed an infection. Other studies were on SBP with 1573 cirrhotic patients with ascites, of whom 557 developed SBP. The pooled results showed that there was no difference in NLR levels between hospitalized cirrhotic patients who developed infection compared to those who did not (random-effects model: SMD = 0.63, 95% CI = -0.01-1.27, Conclusion: Our results support NLR to be a valid biomarker that can be readily integrated into clinical settings to help in the prevention and prediction of SBP among cirrhotic patients.

Indexed as

AscitesPeritonitisBiomarkersHumansLiver CirrhosisLymphocytesNeutrophilsProspective StudiesRetrospective StudiesBiomarkers

Identifiers

PMID36204262
PMCPMC9532151

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.