Evidence map›Paper›PMID 36204236›Full record

ArticleFrontiers in pharmacology2022

A novel phenolic derivative inhibits AHL-dependent quorum sensing signaling in

Giulia Bernabè, Giovanni Marzaro, Giuseppe Di Pietra, Ana Otero, Massimo Bellato, Anthony Pauletto, Melania Scarpa, Stefania Sut, Adriana Chilin, Stefano Dall'Acqua and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
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  5. Broadly Defined Antibiotic Adjuvants forThe Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2026
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  7. Article
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  14. Anti-Biofilm Agents to OvercomePharmaceuticals (Basel, Switzerland) · 2025
    Review
  15. Beyond Antibiotics: What the Future Holds.Antibiotics (Basel, Switzerland) · 2024
    Review
  16. Article
  17. Evaluation of novel compounds as anti-bacterial or anti-virulence agents.Frontiers in cellular and infection microbiology · 2024
    Review
  18. Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Giulia BernabèDepartment of Molecular Medicine, University of Padua, Padua, Italy.
Giovanni MarzaroDepartment of Pharmaceutical and Pharmacological Sciences, University of Padua, Padua, Italy.
Giuseppe Di PietraDepartment of Molecular Medicine, University of Padua, Padua, Italy.
Ana OteroDepartamento de Microbioloxía e Parasitoloxía, Facultade de Bioloxía-CIBUS, Universidade de Santiago de Compostela, Santiago de Compostela, Spain.
Massimo BellatoDepartment of Information Engineering, University of Padua, Padua, Italy.
Anthony PaulettoDepartment of Molecular Medicine, University of Padua, Padua, Italy.
Melania ScarpaLaboratory of Advanced Translational Research, Veneto Institute of Oncology IOV-IRCCS, Padua, Italy.
Stefania SutDepartment of Pharmaceutical and Pharmacological Sciences, University of Padua, Padua, Italy.
Adriana ChilinDepartment of Pharmaceutical and Pharmacological Sciences, University of Padua, Padua, Italy.
Stefano Dall'AcquaDepartment of Pharmaceutical and Pharmacological Sciences, University of Padua, Padua, Italy.
Paola BrunDepartment of Molecular Medicine, University of Padua, Padua, Italy.
Ignazio CastagliuoloDepartment of Molecular Medicine, University of Padua, Padua, Italy.
University of Padua · ITIstituto Oncologico Veneto · ITUniversidade de Santiago de Compostela · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Increasing antibiotic resistance and the decline in the pharmaceutical industry's investments have amplified the need for novel treatments for multidrug-resistant bacteria. Quorum sensing (QS) inhibitors reduce pathogens' virulence without selective pressure on bacteria and provide an alternative to conventional antibiotic-based therapies.

Indexed as

antibiotic resistancebiofilmmolecular dockingquorum sensing inhibitorsvirulence

Identifiers

PMID36204236
PMCPMC9531014
OpenAlexW4296482271

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.