Evidence map›Paper›PMID 36204227›Full record

ArticleFrontiers in pharmacology2022

Protease-activated receptor 2 promotes clearance of

Sheikh Rayees, Jagdish Chandra Joshi, Bhagwati Joshi, Vigneshwaran Vellingiri, Somenath Banerjee, Dolly Mehta

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. TRPV4 facilitates the reprogramming of inflamed macrophages by regulating IL-10 production via CREB.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2024
    Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Sheikh RayeesDepartment of Pharmacology and Regenerative Medicine, Centre for Lung and Vascular Biology, College of Medicine, University of Illinois, Chicago, IL, United States.
Jagdish Chandra JoshiDepartment of Pharmacology and Regenerative Medicine, Centre for Lung and Vascular Biology, College of Medicine, University of Illinois, Chicago, IL, United States.
Bhagwati JoshiDepartment of Pharmacology and Regenerative Medicine, Centre for Lung and Vascular Biology, College of Medicine, University of Illinois, Chicago, IL, United States.
Vigneshwaran VellingiriDepartment of Pharmacology and Regenerative Medicine, Centre for Lung and Vascular Biology, College of Medicine, University of Illinois, Chicago, IL, United States.
Somenath BanerjeeDepartment of Pharmacology and Regenerative Medicine, Centre for Lung and Vascular Biology, College of Medicine, University of Illinois, Chicago, IL, United States.
Dolly MehtaDepartment of Pharmacology and Regenerative Medicine, Centre for Lung and Vascular Biology, College of Medicine, University of Illinois, Chicago, IL, United States.
University of Illinois Chicago · USUniversity of Illinois Urbana-Champaign · US

Funding

Synthetic Biology and Optogenetics CoreP01HL151327 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI REHMAN, JALEES · 2021 to 2025
$11.8M
Focal Adhesion Kinase Regulation of Lung Vascular Permeability and EdemagenesisR01HL084153 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI MEHTA, DOLLY · 2007 to 2022
$5.4M
Mechanisms of endothelial regeneration and resolution of lung vascular injuryR01HL137169 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI MEHTA, DOLLY · 2017 to 2020
$2.1M
CREB Instruction of Macrophage Fate and Lung fluid homeostasisR01HL155941 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI MEHTA, DOLLY · 2021 to 2024
$636k
NHLBI NIH HHS P01 HL151327NHLBI NIH HHS R01 HL084153NHLBI NIH HHS R01 HL137169NHLBI NIH HHS R01 HL155941
6 · The paper itself

Abstract

Efficient phagocytosis of pathogens by the innate immune system during infectious injury is vital for restoring tissue integrity. Impaired phagocytosis, such as in the case of infection with

Indexed as

acute lung injuryalveolar macrophagecAMPPAR2Pseudomonas aeruginosaRac1

Identifiers

PMID36204227
PMCPMC9530345
OpenAlexW4297905720

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.