Evidence map›Paper›PMID 36204177›Full record

ArticleJournal of oncology2022

The Prognostic Value of Serum Apolipoprotein A-I Level and Neutrophil-to-Lymphocyte Ratio in Colorectal Cancer Liver Metastasis.

Chongkai Fang, Yue Huang, Chuyao Chen, Duorui Nie, Jietao Lin, Zhiwei Xiao, Saimei Li, Silin Liu, Rui Luo, Hongtong Lin and 3 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
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  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Chongkai FangFirst Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, 510403 Guangdong, China.ORCID https://orcid.org/0000-0001-8319-5189
Yue HuangFirst Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, 510403 Guangdong, China.ORCID https://orcid.org/0000-0002-2174-301X
Chuyao ChenFirst Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, 510403 Guangdong, China.ORCID https://orcid.org/0000-0003-3449-219X
Duorui NieFirst Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, 510403 Guangdong, China.ORCID https://orcid.org/0000-0003-3412-1196
Jietao LinCancer Center, First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510405 Guangdong, China.ORCID https://orcid.org/0000-0002-5507-3499
Zhiwei XiaoCancer Center, First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510405 Guangdong, China.ORCID https://orcid.org/0000-0001-5522-2813
Saimei LiDepartment of Endocrinology, First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510405 Guangdong, China.ORCID https://orcid.org/0000-0002-5119-1412
Silin LiuFirst Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, 510403 Guangdong, China.ORCID https://orcid.org/0000-0001-6531-5511
Rui LuoFirst Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, 510403 Guangdong, China.ORCID https://orcid.org/0000-0001-9626-987X
Hongtong LinGuangdong Provincial Hospital of Traditional Chinese Medicine, Guangzhou, 510120 Guangdong, China.ORCID https://orcid.org/0000-0003-4843-0678
Chong ZhongLingnan Medical Research Center of Guangzhou University of Chinese Medicine, Guangzhou, 510403 Guangdong, China.ORCID https://orcid.org/0000-0003-4199-0509
Xuewu HuangCancer Center, First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510405 Guangdong, China.ORCID https://orcid.org/0000-0003-2792-5540
Cui ShaoLingnan Medical Research Center of Guangzhou University of Chinese Medicine, Guangzhou, 510403 Guangdong, China.ORCID https://orcid.org/0000-0002-5651-5252
Guangzhou University of Chinese Medicine · CNFirst Affiliated Hospital of Guangzhou University of Chinese Medicine · CNGuangdong Provincial Hospital of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Colorectal cancer liver metastasis (CRLM) is a high degree of malignancy with rapid disease progression and has a poor prognosis. Both serum apolipoprotein A-I (ApoA-I) and neutrophil-to-lymphocyte ratio (NLR) play key roles in anti-inflammation and antitumor. This study is aimed at evaluating the implication of serum ApoA-I level in combination with NLR in the prognosis of CRLM. Methods: We retrospectively analyzed the serum ApoA-I level and NLR in 237 patients with CRLM. Cox regression analyses were used to identify the independent prognostic significance of these indicators. Kaplan-Meier method and Log-rank test were applied to compute overall survival (OS). Both the ApoA-I and NLR were divided into three levels, according to their medians. A risk-stratified prediction model was established to evaluate the prognosis of patients with CRLM. The ROC curve AUC values were applied to evaluate the capability of the model. Results: Higher levels of ApoA-I and lower NLR were strongly associated with prolonged OS (Log-rank test, Conclusion: The combination of ApoA-I level and NLR could be a prognostic indicator for CRLM.

Identifiers

PMID36204177
PMCPMC9532097
OpenAlexW4297342102

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.