Evidence map›Paper›PMID 36204117›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2022

Molecular Characterization of Gene-Mediated Resistance and Susceptibility of ESKAPE Clinical Isolates to

Imane Zalegh, Mohammed Bourhia, Khalid Zerouali, Khalid Katfy, Kaotar Nayme, Farid Khallouki, Ihssane Benzaarate, Ahmad Mohammad Salamatullah, Abdulhakeem Alzahrani, Hiba-Allah Nafidi and 2 more

Open access · hybridAbstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Frontiers in pharmacology · 2026
    Review
  3. Assessment of the Antimicrobial Activity ofInternational journal of molecular sciences · 2025
    Article
  4. Article
  5. Biology, Antioxidant Activity, and Therapeutic Potential ofInternational journal of molecular sciences · 2025
    Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 2 countries.

Imane ZaleghRU Microbiology, Biomolecules and Biotechnology, Laboratory of Chemistry-Physics and Biotechnologies of Biomolecules and Materials, FST Mohammedia, Hassan II University of Casablanca, Casablanca, Morocco.ORCID https://orcid.org/0000-0003-1390-8248
Mohammed BourhiaHigher Institute of Nursing Professions and Technical Health, Laayoune 70000, Morocco.ORCID https://orcid.org/0000-0003-3707-8461
Khalid ZeroualiLaboratory of Microbiology-CHU Ibn Rochd Casablanca, Casablanca, Morocco.ORCID https://orcid.org/0000-0003-4997-2348
Khalid KatfyLaboratory of Microbiology-CHU Ibn Rochd Casablanca, Casablanca, Morocco.
Kaotar NaymeMolecular Bacteriology Laboratory, Institute Pasteur Du Marocco, 1 Place Louis Pasteur, Casablanca 20360, Morocco.
Farid KhalloukiBiology Department, FSTE, University Moulay Ismail, BP. 609, Errachidia 52000, Morocco.
Ihssane BenzaarateMicrobiology, Health and Environment Team Research, Department of Biology, Faculty of Sciences, Chouaib Doukkali University, Route Ben Maachou, El Jadida 24000, Morocco.
Ahmad Mohammad SalamatullahDepartment of Food Science & Nutrition, College of Food and Agricultural Sciences, King Saud University, P.O. Box 2460, Riyadh 11451, Saudi Arabia.ORCID https://orcid.org/0000-0003-1685-1400
Abdulhakeem AlzahraniDepartment of Food Science & Nutrition, College of Food and Agricultural Sciences, King Saud University, P.O. Box 2460, Riyadh 11451, Saudi Arabia.ORCID https://orcid.org/0000-0002-6103-4269
Hiba-Allah NafidiDepartment of Food Science, Faculty of Agricultural and Food Sciences, 2325 University Street Quebec City, Quebec City G1V 0A6, Canada.
Mohamed AkssiraRU Microbiology, Biomolecules and Biotechnology, Laboratory of Chemistry-Physics and Biotechnologies of Biomolecules and Materials, FST Mohammedia, Hassan II University of Casablanca, Casablanca, Morocco.ORCID https://orcid.org/0000-0001-8867-2837
Rajaa Ait MhandRU Microbiology, Biomolecules and Biotechnology, Laboratory of Chemistry-Physics and Biotechnologies of Biomolecules and Materials, FST Mohammedia, Hassan II University of Casablanca, Casablanca, Morocco.ORCID https://orcid.org/0000-0003-1473-0867
University of Hassan II Casablanca · MACentre Hospitalier Universitaire Ibn Rochd · MAKing Saud University · SAChouaib Doukkali University · MAInstitut Pasteur du Maroc · MAInstituts Supérieurs des Professions Infirmières et Techniques de Santé · MA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Multidrug resistance (MDR) and extensively drug-resistant (XDR) are now the biggest threats to human beings. Alternative antimicrobial regimens to conventional antibiotic paradigms are extensively searched. Although Methods: Antibiotic susceptibility profile and resistance mechanism were done by antibiogram and PCR. Fractions of CM and CS were obtained using maceration and Soxhlet; their antibacterial activities were evaluated by determining inhibition zone diameter (IZD), minimum inhibitory concentration (MIC), and minimum bactericidal concentration (MBC). Results: Results revealed that all strains were XDR except Conclusions: The superior activity of extracts to conventional antibiotics was seen for the first time in the pathogens group, and their bactericidal effect could be a promising alternative for developing clinical antibacterial agents against MDR and XDR ESKAPE bacteria.

Identifiers

PMID36204117
PMCPMC9532067
OpenAlexW4297346142

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.