Evidence map›Paper›PMID 36203983›Full record

ArticleFrontiers in neurology2022

The human placenta as a model for training and research in mechanical thrombectomy: Clarifications and use of the chorionic plate veins.

Julien Burel, Jonathan Cornacchini, Matthieu Garnier, Sophie Patrier, Albane Guigné, Emmanuel Gerardin, Chrysanthi Papagiannaki, Nader Sourour, Eimad Shotar, Kévin Premat and 2 more

Abstract read
In one paragraph

Article in Frontiers in neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Julien BurelDepartment of Radiology, Rouen University Hospital, Rouen, France.
Jonathan CornacchiniDepartment of Pathology, Rouen University Hospital, Rouen, France.
Matthieu GarnierDepartment of Radiology, Rouen University Hospital, Rouen, France.
Sophie PatrierDepartment of Pathology, Rouen University Hospital, Rouen, France.
Albane GuignéDepartment of Pathology, Rouen University Hospital, Rouen, France.
Emmanuel GerardinDepartment of Radiology, Rouen University Hospital, Rouen, France.
Chrysanthi PapagiannakiDepartment of Radiology, Rouen University Hospital, Rouen, France.
Nader SourourDepartment of Neuroradiology, Pitié-Salpêtrière Hospital, APHP, Sorbonne University, Paris, France.
Eimad ShotarDepartment of Neuroradiology, Pitié-Salpêtrière Hospital, APHP, Sorbonne University, Paris, France.
Kévin PrematDepartment of Neuroradiology, Pitié-Salpêtrière Hospital, APHP, Sorbonne University, Paris, France.
Claire LaporteDepartment of Pathology, Rouen University Hospital, Rouen, France.
Frédéric ClarençonGRC BioFast, Sorbonne University, Paris, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Indications for mechanical thrombectomy in acute ischemic stroke are increasing, resulting in the continuous development of new devices and techniques. Therefore, there is a need for a realistic testing and training environment that offers the opportunity to practice different procedures and test the latest devices. Some authors have described the use of the human placenta as a model for neurointerventional surgery, with striking similarities to real-life conditions. This model has many advantages, including its relatively low cost and minimal infrastructure requirements, with fewer ethical concerns compared to animal models. So far, some preparation and set-up details were missing, and only arteries from the chorionic plate were used. This article provides the necessary clarifications and a mapping of the chorionic plate veins, so that the use of this model, which is particularly well suited for mechanical thrombectomy, can be as easy and wide as possible. A video explaining how to prepare the model is provided.

Indexed as

interventional neuroradiologymechanical thrombectomyplacentastrokevascular model

Identifiers

PMID36203983
PMCPMC9530792

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.