Evidence map›Paper›PMID 36203971›Full record

ReviewFrontiers in neurology2022

Immune response treated with bone marrow mesenchymal stromal cells after stroke.

Zili Wang, Xudong Wang, Yidong Liao, Guangtang Chen, Kaya Xu

Abstract readReview
In one paragraph

Review in Frontiers in neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Zili WangDepartment of Neurosurgery, The Affiliated Hospital of Guizhou Medical University, Guiyang, China.
Xudong WangDepartment of Neurosurgery, The Affiliated Hospital of Guizhou Medical University, Guiyang, China.
Yidong LiaoDepartment of Neurosurgery, The Affiliated Hospital of Guizhou Medical University, Guiyang, China.
Guangtang ChenDepartment of Neurosurgery, The Affiliated Hospital of Guizhou Medical University, Guiyang, China.
Kaya XuDepartment of Neurosurgery, The Affiliated Hospital of Guizhou Medical University, Guiyang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stroke is a leading cause of death and long-term disability worldwide. Tissue plasminogen activator (tPA) is an effective treatment for ischemic stroke. However, only a small part of patients could benefit from it. Therefore, finding a new treatment is necessary. Bone marrow mesenchymal stromal cells (BMSCs) provide a novel strategy for stroke patients. Now, many patients take stem cells to treat stroke. However, the researches of the precise inflammatory mechanism of cell replacement treatment are still rare. In this review, we summarize the immune response of BMSCs treated to stroke and may provide a new perspective for stem cell therapy.

Indexed as

bone marrow mesenchymal stromal cellinflammationneuroprotectionstem cell therapystroke

Identifiers

PMID36203971
PMCPMC9530191

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.