Evidence map›Paper›PMID 36203835›Full record

ArticleFrontiers in psychiatry2022

The inconsistent mediating effect of catechol

Hang Xu, Yongjie Zhou, Meihong Xiu, Dachun Chen, Weiwen Wang, Li Wang, Xiangyang Zhang

Abstract read
In one paragraph

Article in Frontiers in psychiatry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hang XuCAS Key Laboratory of Mental Health, Institute of Psychology, Beijing, China.
Yongjie ZhouDepartment of Psychiatric Rehabilitation, Shenzhen Kangning Hospital, Shenzhen, Guangdong, China.
Meihong XiuBeijing HuiLongGuan Hospital, Peking University, Beijing, China.
Dachun ChenBeijing HuiLongGuan Hospital, Peking University, Beijing, China.
Weiwen WangCAS Key Laboratory of Mental Health, Institute of Psychology, Beijing, China.
Li WangCAS Key Laboratory of Mental Health, Institute of Psychology, Beijing, China.
Xiangyang ZhangCAS Key Laboratory of Mental Health, Institute of Psychology, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Schizophrenia is a multifaceted mental disorder characterized by heterogeneous positive/negative symptoms and cognitive deficits. Sex differences have been reported in various aspects of the disease. However, the underlying genetic reasons remain unelucidated. Recent studies show that the influence of Materials and methods: We recruited 367 in patients with chronic schizophrenia (246 males and 121 females) and 419 healthy controls (172 males and 247 females). The cognitive performance was assessed by Repeatable Battery for the Assessment of Neuropsychological Status (RBANS), and the Results: We find that male patients had a significantly higher proportion of carrying the Val allele and Val/Val carriers exhibited more severe positive symptoms and cognitive impairment than Met carriers. Conclusion: These findings suggest that

Indexed as

catechol-O-methyl transferase (COMT)cognitive functionschizophreniasex differenceVal158Met (rs4680)

Identifiers

PMID36203835
PMCPMC9531860

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.