Evidence map›Paper›PMID 36203580›Full record

ArticleFrontiers in immunology2022

Intracellular survival of

Tinashe K Nyazika, Lusako Sibale, Joseph Phiri, Megan De Ste Croix, Zydrune Jasiunaite, Christopher Mkandawire, Rose Malamba, Anstead Kankwatira, Miriam Manduwa, Daniela M Ferreira and 4 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 3 countries.

Tinashe K NyazikaMalawi-Liverpool-Wellcome Trust Clinical Research Programme, University of Malawi College of Medicine, Blantyre, Malawi.
Lusako SibaleMalawi-Liverpool-Wellcome Trust Clinical Research Programme, University of Malawi College of Medicine, Blantyre, Malawi.
Joseph PhiriMalawi-Liverpool-Wellcome Trust Clinical Research Programme, University of Malawi College of Medicine, Blantyre, Malawi.
Megan De Ste CroixDepartment of Genetics and Genome Biology, University of Leicester, Leicester, United Kingdom.
Zydrune JasiunaiteDepartment of Genetics and Genome Biology, University of Leicester, Leicester, United Kingdom.
Christopher MkandawireMalawi-Liverpool-Wellcome Trust Clinical Research Programme, University of Malawi College of Medicine, Blantyre, Malawi.
Rose MalambaMalawi-Liverpool-Wellcome Trust Clinical Research Programme, University of Malawi College of Medicine, Blantyre, Malawi.
Anstead KankwatiraMalawi-Liverpool-Wellcome Trust Clinical Research Programme, University of Malawi College of Medicine, Blantyre, Malawi.
Miriam ManduwaMalawi-Liverpool-Wellcome Trust Clinical Research Programme, University of Malawi College of Medicine, Blantyre, Malawi.
Daniela M FerreiraDepartment of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.
Tonney S NyirendaDepartment of Pathology, College of Medicine, University of Malawi, Blantyre, Malawi.
Marco R OggioniDepartment of Genetics and Genome Biology, University of Leicester, Leicester, United Kingdom.
Henry C MwandumbaMalawi-Liverpool-Wellcome Trust Clinical Research Programme, University of Malawi College of Medicine, Blantyre, Malawi.
Kondwani C JamboMalawi-Liverpool-Wellcome Trust Clinical Research Programme, University of Malawi College of Medicine, Blantyre, Malawi.
University of Malawi · MWUniversity of Leicester · GBUniversity of Liverpool · GBLiverpool School of Tropical Medicine · GBMalawi-Liverpool-Wellcome Trust Clinical Research Programme · MW

Funding

Medical Research Council MR/P020526/1Medical Research Council MR/T008822/1Wellcome Trust
6 · The paper itself

Abstract

People Living with HIV (PLHIV) are at an increased risk of pneumococcal pneumonia than HIV-uninfected adults, but the reasons for this are still not well understood. We investigated whether alveolar macrophages (AM) mediated control of pneumococcal infection is impaired in PLHIV compared to HIV-uninfected adults. We assessed anti-bactericidal activity against

Indexed as

HIV InfectionsPneumococcal InfectionsPneumonia, PneumococcalAdultHumansMacrophages, AlveolarStreptococcus pneumoniaealveolar macrophagesHIVintracellular killinglungStreptococcus pneumoniae

Identifiers

PMID36203580
PMCPMC9531125
OpenAlexW4297906274

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.