Evidence map›Paper›PMID 36203568›Full record

Trial reportFrontiers in immunology2022

Complement-mediated serum bactericidal activity of antibodies elicited by the

Melissa C Kapulu, Usman Nakakana, Antonella S Sciré, Eleanna Sarakinou, Valentino Conti, Omar Rossi, Alessandra Acquaviva, Francesca Necchi, Christina W Obiero, Laura B Martin and 4 more

Open access · goldAbstract readClinical Trial, Phase IIRandomized Controlled Trial
In one paragraph

Trial report in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 22 citations in OpenAlex.

  1. Trial
  2. Human vaccines & immunotherapeutics · 2026
    Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Oral immunization withmSphere · 2024
    Article
  10. Article
  11. Outer Membrane Vesicle Vaccine Platforms.BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy · 2024
    Review
  12. Age-dependent acquisition of IgG antibodies toFrontiers in immunology · 2024
    Article
  13. Article
  14. Review
  15. Toward aInternational journal of molecular sciences · 2023
    Review
  16. Article
  17. Functional assays to evaluate antibody-mediated responses againstFrontiers in cellular and infection microbiology · 2023
    Review
  18. Comparison ofFrontiers in molecular biosciences · 2023
    Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 3 countries.

Melissa C KapuluKenya Medical Research Institute (KEMRI)-Wellcome Trust Programme, Kilifi, Kenya.
Usman NakakanaGSK Vaccines Institute for Global Health, Siena, Italy.
Antonella S SciréGSK Vaccines Institute for Global Health, Siena, Italy.
Eleanna SarakinouGSK Vaccines Institute for Global Health, Siena, Italy.
Valentino ContiGSK Vaccines Institute for Global Health, Siena, Italy.
Omar RossiGSK Vaccines Institute for Global Health, Siena, Italy.
Alessandra AcquavivaGSK Vaccines Institute for Global Health, Siena, Italy.
Francesca NecchiGSK Vaccines Institute for Global Health, Siena, Italy.
Christina W ObieroClinical Research Department, KEMRI-Wellcome Trust Programme, Kilifi, Kenya.
Laura B MartinGSK Vaccines Institute for Global Health, Siena, Italy.
Philip BejonKenya Medical Research Institute (KEMRI)-Wellcome Trust Programme, Kilifi, Kenya.
Patricia NjugunaClinical Research Department, KEMRI-Wellcome Trust Programme, Kilifi, Kenya.
Francesca MicoliGSK Vaccines Institute for Global Health, Siena, Italy.
Audino PoddaGSK Vaccines Institute for Global Health, Siena, Italy.
Toscana Life Sciences · ITKenya Medical Research Institute · KE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Dysentery, BacillaryShigellaVaccinesAdultAntibodies, BacterialChildChild, PreschoolHumansImmunoglobulin GKenyaLipopolysaccharidesMethylmethacrylatesO AntigensShigella sonneiAntibodies, Bacterialglyceryl methyl methacrylateImmunoglobulin GLipopolysaccharidesMethylmethacrylatesO AntigensVaccines1790GAHB vaccinefunctional antibodygeneralized modules for membrane antigens (GMMA)IgGkenyan adultsserum bactericidal activityshigella sonnei

Identifiers

PMID36203568
PMCPMC9531247
OpenAlexW4296095872

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.