Evidence map›Paper›PMID 36203440›Full record

ArticleFrontiers in oncology2022

Construction of immune cell infiltration protein network based on clinical low grade glioma cases.

Wei Jiang, Zijian He, Weizhong Jiang, Jiarui Du, Lutao Yuan, Cong Luo, Xiang Li, Fulin Xu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Wei JiangDepartment of Neurosurgery, Minhang Hospital, Fudan University, Shanghai, China.
Zijian HeDepartment of Neurosurgery, Minhang Hospital, Fudan University, Shanghai, China.
Weizhong JiangDepartment of Neurosurgery, Minhang Hospital, Fudan University, Shanghai, China.
Jiarui DuDepartment of Neurosurgery, Minhang Hospital, Fudan University, Shanghai, China.
Lutao YuanDepartment of Neurosurgery, Minhang Hospital, Fudan University, Shanghai, China.
Cong LuoDepartment of Neurosurgery, Minhang Hospital, Fudan University, Shanghai, China.
Xiang LiDepartment of Critical Care Medicine, Minhang Hospital, Fudan University, Shanghai, China.
Fulin XuDepartment of Neurosurgery, Minhang Hospital, Fudan University, Shanghai, China.
Fudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Many researchers have studied low-grade glioma and the immune microenvironment have been studied by many researchers. Recent studies suggest that macrophages and dendritic cells trigger part of the local immune dysregulation in the tumor microenvironment, and they have been polarized into a mixed pro-inflammatory and immunosuppressive phenotype. It is suggested that the degree of immune infiltration is related to the survival, therapeutic effect, and prognosis of patients. This opens up new avenues for cancer treatment. On the basis of immune infiltration degree, a protein interaction network (PIN) and a prognosis model were established, and we chose the top 20 pathways from enrichment analysis to provide potential targets for glioma clinical treatment.

Indexed as

germinal signal analysisgliomaimmune infiltrationPIN (protein interaction network)protein network

Identifiers

PMID36203440
PMCPMC9530812
OpenAlexW4297906686

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.