Evidence map›Paper›PMID 36203350›Full record

ArticleEuropean journal of pain (London, England)2023

How negative and positive constructs and comorbid conditions contribute to disability in chronic orofacial pain.

Sharon Thomas, Yang Wang, Rachel Cundiff-O'Sullivan, Rachel Massalee, Luana Colloca

Open access · greenAbstract read
In one paragraph

Article in European journal of pain (London, England), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Sharon ThomasPain and Translational Symptom Science, University of Maryland School of Nursing, Baltimore, Maryland, USA.ORCID 0000-0001-9455-9056
Yang WangPain and Translational Symptom Science, University of Maryland School of Nursing, Baltimore, Maryland, USA.
Rachel Cundiff-O'SullivanPlacebo Beyond Opinions (PBO) Center, School of Nursing, University of Maryland, Baltimore, Maryland, USA.
Rachel MassaleePain and Translational Symptom Science, University of Maryland School of Nursing, Baltimore, Maryland, USA.
Luana CollocaPain and Translational Symptom Science, University of Maryland School of Nursing, Baltimore, Maryland, USA.ORCID 0000-0002-6503-4709
University of Maryland, Baltimore · US

Funding

Neural correlates of hypoalgesia driven by observationR01AT010333 · NCCIH · UNIVERSITY OF MARYLAND BALTIMORE · PI COLLOCA, LUANA · 2019 to 2023
$3.7M
Neural Mechanisms of Immersive Virtual Reality in Chronic PainR01AT011347 · NCCIH · UNIVERSITY OF MARYLAND BALTIMORE · PI Luana Colloca · 2021 to 2026
$3.2M
Chronic orofacial pain: genetics, cognitive-emotional factors, and endogenous modulatory systemsR01DE025946 · NIDCR · UNIVERSITY OF MARYLAND BALTIMORE · PI COLLOCA, LUANA · 2016 to 2019
$2.1M
Secondary Analysis and Integration of Existing Data Related to Chronic Orofacial Pain and Placebo Effects - Administrative SupplementR21DE032532 · NIDCR · UNIVERSITY OF MARYLAND BALTIMORE · PI COLLOCA, LUANA, DORSEY, SUSAN G · 2022 to 2023
$513k
NCCIH NIH HHS R01 AT010333NCCIH NIH HHS R01 AT011347NIDCR NIH HHS R01 DE025946NIDCR NIH HHS R21 DE032532
6 · The paper itself

Abstract

backgroundTemporomandibular disorders (TMD) symptoms develop into chronic pain for some patients, but the reasons for this are unclear. Psychosocial factors and chronic overlapping pain conditions are believed to contribute to the development of pain-related disability. We examined the role of jaw function, negative and positive psychological factors and chronic overlapping pain conditions (COPCs) on pain-related disability whilst controlling for demographic variables.

methodsWe collected demographics, medical and psychosocial history and the Graded Chronic Pain Scale, a measure of pain intensity and pain interference from 400 participants with chronic TMD. Structural equation modelling was used to assess a model of COPCs and the latent variables of psychological unease (pain catastrophizing, somatic symptoms and negative affect), positive valence factors (optimism and positive affect), jaw function (chewing, opening and expression limitation) and pain-related disability (pain intensity and pain interference) whilst controlling for demographic variables.

resultsWe achieved good fit of a parsimonious model (root-mean-square error of approximation = 0.063 [90% CI] [0.051-0.075]), comparative fit index = 0.942, standard root-mean-square residual = 0.067. Jaw function was the strongest latent variable predictor, followed by psychological unease and COPCs suggesting resources focused on improving joint function, psychosocial support and management of COPCs will improve pain-related disability in TMDs.

conclusionsThese findings not only increase the body of knowledge related to TMD clinical phenotypes but also, have a translational impact in further supporting the potential value of targeting physical therapy such as jaw exercise along with psychological interventions as multidisciplinary nonpharmacological therapeutic solutions.

Indexed as

Chronic PainTemporomandibular Joint DisordersChronic DiseaseFacial PainHumansPain Measurement

Identifiers

PMID36203350
PMCPMC9799734
OpenAlexW4303044316

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.