SynthesisActa paediatrica (Oslo, Norway : 1992)2023
Growth and risk of adverse neuro-developmental outcome in infants with congenital heart disease: A systematic review.
Synthesis in Acta paediatrica (Oslo, Norway : 1992), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 27 citations in OpenAlex.
- Growth after pediatric and neonatal acute kidney injury: a meta-analysis.Pediatric nephrology (Berlin, Germany) · 2025Pooled it
- Growth and risk of adverse neuro-developmental outcome in infants with congenital heart disease: A systematic review.Acta paediatrica (Oslo, Norway : 1992) · 2023Pooled it
- The Use of Dapagliflozin in Infants and Children with Heart Failure.Pediatric cardiology · 2026Article
- Severity of Congenital Heart Defects Affects Long-Term Somatic Development.Pediatric cardiology · 2026Article
- Factors associated with preterm birth and low birth weight among infants with congenital heart disease in Changsha City, China, 2022-2024.Scientific reports · 2026Article
- Article
- From toddler to school age: longitudinal motor and cognitive outcomes in children with critical congenital heart disease.Frontiers in pediatrics · 2026Article
- A novel nomogram for predicting early postoperative cerebral desaturation events after congenital heart surgery.Frontiers in surgery · 2026Article
- Growth Characteristics at Time of Fontan Procedure and Their Association with Long-Term Outcomes.The Journal of pediatrics · 2025Article
- A case report of spastic diplegic cerebral palsy in a late preterm child with hypoplastic left heart syndrome.Translational pediatrics · 2024Article
- The impact of maternal intrahepatic cholestasis during pregnancy on the growth trajectory of offspring: a population-based nested case‒control cohort study.BMC pregnancy and childbirth · 2024Article
- Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimCongenital heart disease (CHD) is one of the most common birth defects affecting around 1:100 infants. In this systematic review, we aimed to determine impact of growth on neurodevelopmental outcomes of infants with CHD.
methodsStudies that reported association of growth with developmental outcomes in infants with CHD who had surgery, were included. The search strategy was prospectively registered. Relevant studies were identified by electronic searches. The Cochrane Central Register of Controlled Trials, MEDLINE and EMBASE were searched from their earliest date to February 2022.
resultsTwenty studies met inclusion criteria. Choice of growth measures, developmental assessment tools and timing of assessment varied widely precluding conduct of a meta-analysis. Seventeen studies reported on infants who had cardio-pulmonary bypass. Birth weight was reported in thirteen studies and was associated with adverse outcome in nine. Head circumference at birth and later predicted developmental outcomes in five. Impaired postnatal growth was associated with adverse developmental outcome in seven studies.
conclusionGrowth in infants with congenital heart disease, specifically single ventricle physiology can predict adverse neurodevelopmental outcome. Included studies showed significant clinical heterogeneity. Uniformity should be agreed by various data registries with routine prospective collection of growth and developmental data.
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