Observational studyBMC cardiovascular disorders2022
Red blood cell distribution width predicts gastrointestinal bleeding after coronary artery bypass grafting.
Observational study in BMC cardiovascular disorders, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 10 citations in OpenAlex.
- Red Cell Distribution Width is Associated with Bleeding Complications after Coronary Artery Bypass Grafting.Interdisciplinary cardiovascular and thoracic surgery · 2026Article
- The Red Blood Cell Distribution Width to Albumin Ratio Is Associated with in Hospital Mortality and Adverse Outcome in Elderly Chinese Patients with Gastrointestinal Bleeding.Journal of inflammation research · 2025Article
- Hemoglobin-to-Red Cell Distribution Width Ratio as a Predictor of Gastrointestinal Bleeding Following Percutaneous Coronary Intervention.Cardiology research and practice · 2025Article
- Red Blood Cell Distribution Width as a Risk Factor for 30/90-Day Mortality in Patients with Gastrointestinal Bleeding: Analysis of the MIMIC-IV Database.Digestive diseases and sciences · 2024Article
- Predictive value of red blood cell distribution width and hematocrit for short-term outcomes and prognosis in colorectal cancer patients undergoing radical surgery.World journal of gastroenterology · 2024Article
- Non-linear relationship between red blood cell distribution width and gastrointestinal bleeding risk in stroke patients: results from multi-center ICUs.Frontiers in neurology · 2024Article
- Relation between red blood cell distribution width and 30-day in-hospital mortality of patients with ventilator-associated pneumonia.BMC infectious diseases · 2023Article
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Authors and funding
12 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRed blood cell distribution width (RDW) is highly associated with adverse clinical outcomes in many diseases. The present study aimed to evaluate the relationship between RDW and gastrointestinal bleeding (GIB) after isolated coronary artery bypass grafting (CABG).
methodsThis was a retrospective observational study that included 4473 patients who received CABG, and all the data were extracted from the Medical Information Mart for Intensive Care III database. Data collected included patient demographics, associated comorbid illnesses, laboratory parameters, and medications. The receiver operating characteristic (ROC) curve was used to determine the best cutoff value of RDW for the diagnosis of GIB. Multivariable logistic regression analysis was used to analyze the relationship between RDW and GIB.
resultsThe incidence of GIB in patients receiving CABG was 1.1%. Quartile analyses showed a significant increase in GIB incidence at the fourth RDW quartile (> 14.3%; P < 0.001). The ROC curve analysis revealed that an RDW level > 14.1% measured on admission had 59.6% sensitivity and 69.4% specificity in predicting GIB after CABG. After adjustment for confounders, high RDW was still associated with an increased risk of GIB in patients with CABG (odds ratio = 2.83, 95% confidence interval 1.46-5.51, P = 0.002).
conclusionsOur study indicates that the elevated RDW level is associated with an increased risk of GIB after CABG, and it can be an independent predictor of GIB. The introduction of RDW to study GIB enriches the diagnosis method of GIB and ensures the rapid and accurate diagnosis of GIB.
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