Evidence map›Paper›PMID 36203124›Full record

ArticleBMC pediatrics2022

Anthropometrics of Polish children with osteogenesis imperfecta: a single-centre retrospective cohort study.

E Jakubowska-Pietkiewicz, A Maćkowska, J Nowicki, E Woźniak, Nowicki Jakub

Open access · goldAbstract read
In one paragraph

Article in BMC pediatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

E Jakubowska-PietkiewiczDepartment of Pediatrics, Newborn Pathology and Bone Metabolic Diseases, University of Lodz, Sporna 36/50, 91-738, Lodz, Poland.
A MaćkowskaDepartment of Pediatrics, Newborn Pathology and Bone Metabolic Diseases, University of Lodz, Sporna 36/50, 91-738, Lodz, Poland.
J NowickiDepartment of Pediatrics, Newborn Pathology and Bone Metabolic Diseases, University of Lodz, Sporna 36/50, 91-738, Lodz, Poland.
E WoźniakDepartment of Pediatrics, Newborn Pathology and Bone Metabolic Diseases, University of Lodz, Sporna 36/50, 91-738, Lodz, Poland.
Nowicki JakubDepartment of Pediatrics, Newborn Pathology and Bone Metabolic Diseases, University of Lodz, Sporna 36/50, 91-738, Lodz, Poland. jakub.nowicki@umed.lodz.pl.
University of Łódź · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOsteogenesis imperfecta (OI) causes a number of abnormalities in somatic development. The predominant symptoms are reduced bone mass and an increased risk of fractures as well as bone deformities and short stature. Due to the lack of causal treatment options, bisphosphonates are considered the gold standard of therapy. The aim of our study is to present selected anthropometric parameters (body weight, height, BMI) in children with type I and III of OI.

methodsWe performed a retrospective analysis of medical records of patients with osteogenesis imperfecta type I and III confirmed by genetic testing. The study group included individuals admitted to the Department in 2020. We analysed the anthropometric parameters of 108 children (receiving and not receiving bisphosphonates treatment).

resultsIn the group of children with OI type I admitted for follow-up (group 1), the median weight percentile was 37, while in the group 2 it was 17. In the patients with OI type III (group 3), the median weight percentile was 0.1. The median height percentile in group 1 was 21, in group 2 it was 5, whereas in group 3 = 0.1. The differences in anthropometric measurements of the patients with OI type I and OI type III were statistically significant (p < 0.001). Among the analysed patients, an abnormal BMI was found in 41.67% of whom 37.78% were underweight, 48.89% were overweight and 13.33% were obese.

conclusionConsidering prevalence of the disease, it is not only low stature but also abnormal BMI, and especially excessive body weight, that play an important role in the somatic development disorder.

Indexed as

Osteogenesis ImperfectaBody WeightChildDiphosphonatesHumansPolandRetrospective StudiesDiphosphonatesBMIBody weightHeightObesityOsteogenesis imperfecta

Identifiers

PMID36203124
PMCPMC9535875
OpenAlexW4302288255

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.