Evidence map›Paper›PMID 36203087›Full record

ArticleCommunications biology2022

Attogram-level light-induced antigen-antibody binding confined in microflow.

Takuya Iida, Shota Hamatani, Yumiko Takagi, Kana Fujiwara, Mamoru Tamura, Shiho Tokonami

Abstract read
In one paragraph

Article in Communications biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Recent development of affinity-based assay systems.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Takuya Iida *Department of Physical Science, Graduate School of Science, Osaka Prefecture University, 1-2 Gakuencho, Nakaku, Sakai, Osaka, 599-8570, Japan. t-iida@omu.ac.jp.ORCID 0000-0003-1313-7025
Shota HamataniDepartment of Physical Science, Graduate School of Science, Osaka Prefecture University, 1-2 Gakuencho, Nakaku, Sakai, Osaka, 599-8570, Japan.
Yumiko TakagiDepartment of Physical Science, Graduate School of Science, Osaka Prefecture University, 1-2 Gakuencho, Nakaku, Sakai, Osaka, 599-8570, Japan.
Kana FujiwaraDepartment of Physical Science, Graduate School of Science, Osaka Prefecture University, 1-2 Gakuencho, Nakaku, Sakai, Osaka, 599-8570, Japan.
Mamoru TamuraResearch Institute for Light-induced Acceleration System (RILACS), Osaka Prefecture University, 1-2 Gakuencho, Nakaku, Sakai, Osaka, 599-8570, Japan.
Shiho Tokonami *Research Institute for Light-induced Acceleration System (RILACS), Osaka Prefecture University, 1-2 Gakuencho, Nakaku, Sakai, Osaka, 599-8570, Japan. tokonami@omu.ac.jp.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The analysis of trace amounts of proteins based on immunoassays and other methods is essential for the early diagnosis of various diseases such as cancer, dementia, and microbial infections. Here, we propose a light-induced acceleration of antigen-antibody reaction of attogram-level proteins at the solid-liquid interface by tuning the laser irradiation area comparable to the microscale confinement geometry for enhancing the collisional probability of target molecules and probe particles with optical force and fluidic pressure. This principle was applied to achieve a 10

Indexed as

Antigen-Antibody ReactionsEarly Detection of CancerImmunoassayProteinsProteins

Identifiers

PMID36203087
PMCPMC9537419

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.