ArticleScientific reports2022
Activating effective functional hand movements in individuals with complete tetraplegia through neural stimulation.
Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Evaluation of Non-invasive Control Interfaces for Operating Assistive Devices for Tetraplegic Individuals
Relevance of Virtual Reality Assessment of Control Interfaces for a Neuroprosthesis That Stimulates the Upper Limbs of Quadriplegic Individuals
Who cites it
7 citing papers in PubMed, 19 citations in OpenAlex.
- Hypoglossal nerve stimulation in a pig model for evaluation of genioglossus muscle force with different stimulation parameters.Scientific reports · 2026Article
- Restoring hand grasping for patients with a complete tetraplegia with selective epineural stimulation: a parsimonious thus relevant clinical approach.Journal of neuroengineering and rehabilitation · 2026Article
- Optimisation and Comparison of Markerless and Marker-Based Motion Capture Methods for Hand and Finger Movement Analysis.Sensors (Basel, Switzerland) · 2025Article
- Electrical stimulation in upper limb assistance: opportunities and challenges.Frontiers in neuroscience · 2025Review
- Electrical Stimulation and Motor Function Rehabilitation in Spinal Cord Injury: A Systematic Review.Cureus · 2024Review
- Biomimetic Peripheral Nerve Stimulation Promotes the Rat Hindlimb Motion Modulation in Stepping: An Experimental Analysis.Cyborg and bionic systems (Washington, D.C.) · 2024Article
- The Easy and Versatile Neural Recording Platform (T-REX): Design and Development Study.JMIR neurotechnology · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Individuals with complete cervical spinal cord injury suffer from a permanent paralysis of upper limbs which prevents them from achieving most of the activities of daily living. We developed a neuroprosthetic solution to restore hand motor function. Electrical stimulation of the radial and median nerves by means of two epineural electrodes enabled functional movements of paralyzed hands. We demonstrated in two participants with complete tetraplegia that selective stimulation of nerve fascicles by means of optimized spreading of the current over the active contacts of the multicontact epineural electrodes induced functional and powerful grasping movements which remained stable over the 28 days of implantation. We also showed that participants were able to trigger the activation of movements of their paralyzed limb using an intuitive interface controlled by voluntary actions and that they were able to perform useful functional movements such as holding a can and drinking through a straw.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.