SynthesisScientific reports2022
Prevalence of potentially inappropriate prescribing in older adults in Central and Eastern Europe: a systematic review and synthesis without meta-analysis.
Synthesis in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 26 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Prevalence of potentially inappropriate medications in people living with HIV: a systematic review and meta-analysis.BMC infectious diseases · 2025Pooled it
- Prevalence of Potentially Inappropriate Prescribing in Older Adults in Gulf Cooperation Council Countries: A Systematic Review and Meta-Analysis.Journal of epidemiology and global health · 2024Pooled it
- Potentially Inappropriate Medication Use in Older Adults in Primary Care According to Four Explicit Criteria: Associations with Patient Factors.Medicina (Kaunas, Lithuania) · 2026Observational
- Potentially inappropriate prescribing in Iranian elderly population: a nationwide claims-based analysis.BMJ open · 2026Observational
- Pharmacists' perceived knowledge, attitudes and practice in geriatrics: findings from a multinational multilingual open online survey.European geriatric medicine · 2026Article
- Tailoring an Implementation Strategy for Deprescribing as Part of a Comprehensive Geriatric Assessment (dCGA) in Long-Term Care Facilities: A Roundtable Discussion.Basic & clinical pharmacology & toxicology · 2026Article
- Use of Potentially Inappropriate Medication and Association with Falls During Hospitalisation: An Analysis Based on Electronic Health Records (POLAR_MI project).Drugs - real world outcomes · 2026Article
- ESCP best practice: development of the national methodology for the provision of clinical-pharmaceutical care and its implementation in the healthcare system of the Czech Republic.International journal of clinical pharmacy · 2025Article
- Assessing potentially inappropriate medication use among older adults in Central and Eastern Europe.Annals of medicine · 2025Article
- Anticholinergic and Sedative Medication Burden in Croatian Older Adults: EuroAgeism Cohort Findings.Pharmacy (Basel, Switzerland) · 2025Article
- A Prospective Study on Potentially Inappropriate Drug Use and All-Cause Mortality in Community-Dwelling Older Adults.Journal of the American Geriatrics Society · 2025Article
- Attitudes, barriers, and facilitators toward tools supporting appropriate prescribing among healthcare professionals: a cross-sectional study.European journal of clinical pharmacology · 2025Article
- Identification of the Potential Pharmacotherapeutic Risk in Hospitalized Geriatric Patients.Cureus · 2025Article
- Impact of a Multidisciplinary Approach to Polypharmacy Management in Community-Dwelling Older Adults: Insights From a Specialized Outpatient Clinic.Aging medicine (Milton (N.S.W)) · 2025Article
- Identification of seniors at risk (ISAR) score and potentially inappropriate prescribing: a retrospective cohort study.International journal of clinical pharmacy · 2024Article
- Prevalence of potentially inappropriate medications and prescription dynamics in elderly hospitalized patients in Spain.BMC geriatrics · 2024Observational
- Potentially Inappropriate Medication Use in Primary Care in Switzerland.JAMA network open · 2024Article
- Deprescribing potential of commonly used medications among community-dwelling older adults: insights from a pharmacist's geriatric assessment.Scientific reports · 2024Article
- Evaluation of medication safety assessment tools for pharmacist-led medication reviews: the Eastern European pilot project.Frontiers in pharmacology · 2024Article
- Potentially inappropriate prescribing in elderly patients with epilepsy at two referral hospitals in Ethiopia.Frontiers in medicine · 2024Article
Corrections and comments
- Erratum issued
Authors and funding
9 authors.
Funding
Abstract
We aimed to systematically review the prevalence of potentially inappropriate prescribing (PIP) in older adults in Central and Eastern Europe (CEE) in all care settings. We searched Embase and MEDLINE (up to June 2019) and checked the reference lists of the included studies and relevant reviews. Eligible studies used validated explicit or implicit tools to assess the PIP prevalence in older adults in CEE. All study designs were considered, except case‒control studies and case series. We assessed the risk of bias using the Joanna Briggs Institute Prevalence Critical Appraisal Tool and the certainty of evidence using the GRADE approach. Meta-analysis was inappropriate due to heterogeneity in the outcome measurements. Therefore, we used the synthesis without meta-analysis approach-summarizing effect estimates method. This review included twenty-seven studies with 139,693 participants. Most studies were cross-sectional and conducted in high-income countries. The data synthesis across 26 studies revealed the PIP prevalence: the median was 34.6%, the interquartile range was 25.9-63.2%, and the range was 6.5-95.8%. The certainty of this evidence was very low due to the risk of bias, imprecision, and inconsistency. These findings show that PIP is a prevalent issue in the CEE region. Further well-designed studies conducted across countries are needed to strengthen the existing evidence and increase the generalizability of findings.
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