Evidence map›Paper›PMID 36202255›Full record

ReviewNeuroscience and biobehavioral reviews2022

Learning from addiction: Craving of prescription opioids in chronic pain sufferers.

Irina A Strigo, Emily Murphy, Jennifer M Mitchell, Andrea D Spadoni

Open access · greenAbstract readReview
In one paragraph

Review in Neuroscience and biobehavioral reviews, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Observational
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Irina A StrigoEmotion and Pain Laboratory, San Francisco Veterans Affairs Healthcare Center, 4150 Clement Street, San Francisco, CA 94121, USA; Department of Psychiatry, University of California San Francisco, 401 Parnassus Ave, San Francisco, CA 94143, USA. Electronic address: Irina.Strigo@ucsf.edu.
Emily MurphyEmotion and Pain Laboratory, San Francisco Veterans Affairs Healthcare Center, 4150 Clement Street, San Francisco, CA 94121, USA.
Jennifer M MitchellDepartment of Psychiatry, University of California San Francisco, 401 Parnassus Ave, San Francisco, CA 94143, USA; Department of Neurology, University of California San Francisco, 401 Parnassus Ave, San Francisco, CA 94143, USA.
Andrea D SpadoniSan Diego Veterans Affairs Healthcare Center, 3350 La Jolla Village Drive, San Diego, CA 92121, USA; Department of Psychiatry, University of California San Diego, San Diego, CA 92300, USA.
University of California, San Francisco · USSan Francisco VA Medical Center · USUniversity of California, San Diego · US

Funding

UCSF Core Center for Patient-centric Mechanistic Phenotyping in Chronic Low Back PainU19AR076737 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KRUG, ROLAND · 2019 to 2023
$34.1M
Neuromarkers of Treatment for Comorbid Posttraumatic Stress Disorder and Alcohol Use DisorderI01CX001762 · VA · VA SAN DIEGO HEALTHCARE SYSTEM · PI SPADONI TOWNSEND, ANDREA · 2019 to 2022
–
CSRD VA I01 CX000816CSRD VA I01 CX001762NIAMS NIH HHS U19 AR076737
6 · The paper itself

Abstract

Prescription opioids are a primary driver of opioid-related deaths. Although craving is a substantial component of OUD, the degree to which craving leads to misuse among chronic pain patients on long-term prescription opioids is unknown. A clear understanding of the factors that lead to misuse in this vulnerable population is needed for the development of safe and effective practices for opioid taper. This narrative review summarizes the relevant literature on the role of craving in addiction and chronic pain through epidemiological and behavioral studies. The first part of this review examines the role of craving in predicting opioid use/misuse in individuals with chronic pain with and without OUD. The second part covers methods on how craving is evaluated experimentally using both subjective and objective measures and provides related findings. The overall goal of this review is to facilitate the development of a population-specific description of craving in those who use opioids to control chronic pain and to describe how it may be mechanistically linked to patterns of opioid (mis)use.

Indexed as

Chronic PainOpioid-Related DisordersAnalgesics, OpioidCravingCuesHumansPrescriptionsAnalgesics, OpioidChronic painCravingCue-reactivityDot-probeInsulaOpioid use disorder

Identifiers

PMID36202255
PMCPMC10917419
OpenAlexW4300716979

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.