Evidence map›Paper›PMID 36201682›Full record

ArticleMolecular pharmaceutics2022

Functionalization of Radiolabeled Antibodies to Enhance Peripheral Clearance for High Contrast Brain Imaging.

Eva Schlein, Stina Syvänen, Johanna Rokka, Tobias Gustavsson, Raffaella Rossin, Marc Robillard, Jonas Eriksson, Dag Sehlin

Open access · hybridAbstract read
In one paragraph

Article in Molecular pharmaceutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Review
  3. Toward Realization of Bioorthogonal Chemistry in the Clinic.Topics in current chemistry (Cham) · 2025
    Review
  4. Nuclear Imaging of Bispecific Antibodies on the Rise.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2024
    Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Eva SchleinDepartment of Public Health and Caring Sciences, Uppsala University, 751 85 Uppsala, Sweden.
Stina SyvänenDepartment of Public Health and Caring Sciences, Uppsala University, 751 85 Uppsala, Sweden.ORCID 0000-0002-8196-4041
Johanna RokkaDepartment of Public Health and Caring Sciences, Uppsala University, 751 85 Uppsala, Sweden.ORCID 0000-0003-3962-696X
Tobias GustavssonDepartment of Public Health and Caring Sciences, Uppsala University, 751 85 Uppsala, Sweden.
Raffaella RossinTagworks Pharmaceuticals, Toernooiveld 1, 6525 ED Nijmegen, Netherlands.
Marc RobillardTagworks Pharmaceuticals, Toernooiveld 1, 6525 ED Nijmegen, Netherlands.ORCID 0000-0002-3690-2087
Jonas ErikssonPET Centre, Uppsala University Hospital, 751 85 Uppsala, Sweden.ORCID 0000-0003-0241-092X
Dag SehlinDepartment of Public Health and Caring Sciences, Uppsala University, 751 85 Uppsala, Sweden.ORCID 0000-0002-9430-3859
Uppsala University · SETagworks Pharmaceuticals (Netherlands) · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Small molecule imaging agents such as [

Indexed as

Alzheimer DiseaseImmunoconjugatesAmyloidAmyloid beta-PeptidesAnimalsAntibodiesBrainDisease ProgressionMannoseMiceMice, TransgenicNeuroimagingPositron-Emission TomographyAmyloidAmyloid beta-PeptidesAntibodiesImmunoconjugatesMannoseAlzheimer’s diseaseantibodyclearing agentinverse electron-demand Diels−Alder reactionmannoseSPECT imagingTCOtetrazine

Identifiers

PMID36201682
PMCPMC9644377
OpenAlexW4302742836

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.