Evidence map›Paper›PMID 36201466›Full record

ArticlePloS one2022

The association between the parameters of uroflowmetry and lower urinary tract symptoms in prostate cancer patients after robot-assisted radical prostatectomy.

Yuta Takeshima, Yuta Yamada, Kotaro Takemura, Naoki Kimura, Yuji Hakozaki, Jimpei Miyakawa, Satoru Taguchi, Yoshiyuki Akiyama, Yusuke Sato, Taketo Kawai and 3 more

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Yuta TakeshimaDivision of Innovative Cancer Therapy, Advanced Research Center, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan.
Yuta YamadaDepartment of Urology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.ORCID 0000-0002-9698-4301
Kotaro TakemuraDepartment of Urology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Naoki KimuraDepartment of Urology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Yuji HakozakiDepartment of Urology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Jimpei MiyakawaDepartment of Urology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Satoru TaguchiDepartment of Urology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.ORCID 0000-0002-1291-4294
Yoshiyuki AkiyamaDepartment of Urology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Yusuke SatoDepartment of Urology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Taketo KawaiDepartment of Urology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Daisuke YamadaDepartment of Urology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Tetsuya FujimuraDepartment of Urology, Jichi Medical University, Tochigi, Japan.
Haruki KumeDepartment of Urology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
The University of Tokyo · JPJichi Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate changes in uroflowmetry parameters in men undergoing robot-assisted radical prostatectomy (RARP) for prostate cancer. MATERIALS AND

methodsFour hundred and twenty-eight patients received uroflowmetry testing before and after RARP from November 2011 to December 2018. Clinicopathological data, including age, initial prostate-specific antigen (PSA), prostate volume, clinical stage, body mass index (BMI), uroflowmetry parameters, and core lower urinary tract symptom scores (CLSS) were retrospectively obtained from clinical records. Changes in uroflowmetry parameters were analyzed for statistical predictors and effects on post-operative outcomes.

resultsA significant increase in maximum flow rate (MFR) and decreases in voided volume (VV) and post-void residual urine (PVR) were seen. In multivariate analysis, age was a negative predictor of MFR increase, while prostate volume was a positive predictor of PVR decrease and MFR increase. VV decrease led to worse incontinence symptoms, while PVR decrease and MFR increase led to improvement in voiding symptoms such as slow stream and straining. Continence recovery curves showed that VV decrease were associated with a delay in continence recovery.

conclusionsSignificant changes were seen in uroflowmetry results after RARP, each parameter directly related to urinary symptoms. In particular, VV decrease was associated with a worsening of incontinence symptoms and continence recovery.

Indexed as

Lower Urinary Tract SymptomsProstatic NeoplasmsRoboticsRobotic Surgical ProceduresUrinary IncontinenceUrinary RetentionHumansMaleProstateProstatectomyProstate-Specific AntigenRetrospective StudiesProstate-Specific Antigen

Identifiers

PMID36201466
PMCPMC9536545
OpenAlexW4302763293

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.