Evidence map›Paper›PMID 36201298›Full record

ReviewAnnual review of cell and developmental biology2022

Neurobiology, Stem Cell Biology, and Immunology: An Emerging Triad for Understanding Tissue Homeostasis and Repair.

Emily Scott-Solomon, Ya-Chieh Hsu

Abstract readReview
In one paragraph

Review in Annual review of cell and developmental biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Review
  8. Article
  9. Review
  10. [Research progress on the role of peripheral nerves in wound healing].Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2025
    Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Emily Scott-SolomonDepartment of Stem Cell and Regenerative Biology, Harvard University, Cambridge, Massachusetts, USA; email: escottsolomon@fas.harvard.edu, yachieh_hsu@harvard.edu.
Ya-Chieh HsuDepartment of Stem Cell and Regenerative Biology, Harvard University, Cambridge, Massachusetts, USA; email: escottsolomon@fas.harvard.edu, yachieh_hsu@harvard.edu.

Funding

Nerve-stem cell interactions during skin homeostasis and wound repairF32AR079252 · NIAMS · HARVARD UNIVERSITY · PI SCOTT-SOLOMON, EMILY RIVKAH · 2021 to 2023
$205k
NIAMS NIH HHS F32 AR079252
6 · The paper itself

Abstract

The peripheral nervous system (PNS) endows animals with the remarkable ability to sense and respond to a dynamic world. Emerging evidence shows the PNS also participates in tissue homeostasis and repair by integrating local changes with organismal and environmental changes. Here, we provide an in-depth summary of findings delineating the diverse roles of peripheral nerves in modulating stem cell behaviors and immune responses under steady-state conditions and in response to injury and duress, with a specific focus on the skin and the hematopoietic system. These examples showcase how elucidating neuro-stem cell and neuro-immune cell interactions provides a conceptual framework that connects tissue biology and local immunity with systemic bodily changes to meet varying demands. They also demonstrate how changes in these interactions can manifest in stress, aging, cancer, and inflammation, as well as how these findings can be harnessed to guide the development of new therapeutics.

Indexed as

NeurobiologyNeuroimmunomodulationAnimalsHomeostasisInflammationStem Cellsinflammationneuro–immune cell interactionneuro–stem cell interactionperipheral nervous systemstem cell nichesystemic regulation

Identifiers

PMID36201298
PMCPMC10085582

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.