Evidence map›Paper›PMID 36200862›Full record

ArticleeLife2022

Single-cell RNA sequencing analysis of shrimp immune cells identifies macrophage-like phagocytes.

Peng Yang, Yaohui Chen, Zhiqi Huang, Huidan Xia, Ling Cheng, Hao Wu, Yueling Zhang, Fan Wang

Open access · goldAbstract read
In one paragraph

Article in eLife, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 39 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Immune cell type divergence in a basal chordate.bioRxiv : the preprint server for biology · 2025
    Article
  11. Article
  12. A new dawn for the study of cell type evolution.Development (Cambridge, England) · 2024
    Review
  13. Article
  14. Review
  15. Article
  16. Review
  17. Article
  18. AnMethodsX · 2023
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 3 countries.

Peng YangInstitute of Marine Sciences, Guangdong Provincial Key Laboratory of Marine Biotechnology, Shantou University, Shantou, China.ORCID 0000-0002-8298-8926
Yaohui ChenDepartment of Biology, College of Science, Shantou University, Shantou, China.ORCID 0000-0002-4044-4373
Zhiqi HuangDepartment of Biology, College of Science, Shantou University, Shantou, China.
Huidan XiaDepartment of Biology, College of Science, Shantou University, Shantou, China.
Ling ChengGuangzhou Genedenovo Biotechnology Company Limited, Guangzhou, China.
Hao WuGuangzhou Genedenovo Biotechnology Company Limited, Guangzhou, China.
Yueling ZhangInstitute of Marine Sciences, Guangdong Provincial Key Laboratory of Marine Biotechnology, Shantou University, Shantou, China.
Fan WangInstitute of Marine Sciences, Guangdong Provincial Key Laboratory of Marine Biotechnology, Shantou University, Shantou, China.ORCID 0000-0002-6059-6956
Shantou University · CNUniversiti Malaysia Terengganu · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite the importance of innate immunity in invertebrates, the diversity and function of innate immune cells in invertebrates are largely unknown. Using single-cell RNA-seq, we identified prohemocytes, monocytic hemocytes, and granulocytes as the three major cell-types in the white shrimp hemolymph. Our results identified a novel macrophage-like subset called monocytic hemocytes 2 (MH2) defined by the expression of certain marker genes, including

Indexed as

Arthropod ProteinsPenaeidaeAnimalsHemocytesImmunity, InnateMacrophagesMammalsNLR Family, Pyrin Domain-Containing 3 ProteinPhagocytesSequence Analysis, RNAArthropod ProteinsNLR Family, Pyrin Domain-Containing 3 Proteindifferentiationimmunologyinflammationinvertebratemacrophagesmyeloid cell evolutionpenaeus vannameiPenaeus vannamei

Identifiers

PMID36200862
PMCPMC9584607
OpenAlexW4302763272

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.