Evidence map›Paper›PMID 36200618›Full record

Observational studyInternational journal of geriatric psychiatry2022

Prevalence and predictors of Motoric Cognitive Risk syndrome in a community-dwelling older Scottish population: A longitudinal observational study.

Donncha S Mullin, Lucy E Stirland, Miles Welstead, Tom C Russ, Michelle Luciano, Graciela Muniz-Terrera

Open access · hybridAbstract readObservational Study
In one paragraph

Observational study in International journal of geriatric psychiatry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
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  5. Physical fitness and incident mild cognitive impairment: a systematic review.European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity · 2025
    Review
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  12. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 3 countries.

Donncha S MullinAlzheimer Scotland Dementia Research Centre, University of Edinburgh, Edinburgh, UK.ORCID 0000-0002-1679-8067
Lucy E StirlandAlzheimer Scotland Dementia Research Centre, University of Edinburgh, Edinburgh, UK.
Miles WelsteadLothian Birth Cohorts, Department of Psychology, University of Edinburgh, Edinburgh, UK.ORCID 0000-0003-4615-2539
Tom C RussAlzheimer Scotland Dementia Research Centre, University of Edinburgh, Edinburgh, UK.
Michelle LucianoLothian Birth Cohorts, Department of Psychology, University of Edinburgh, Edinburgh, UK.
Graciela Muniz-TerreraEdinburgh Dementia Prevention Group, University of Edinburgh, Edinburgh, UK.
NHS Lothian · GBAdolfo Ibáñez University · CL

Funding

Medical Research Council MR/J000914/1Medical Research Council MR/K026992/1MRF_ C0396
6 · The paper itself

Abstract

objectivesMotoric Cognitive Risk (MCR) is a gait-based predementia syndrome that is easy to measure and prognostic of dementia and falls. We aimed to examine the prevalence and risk factors for MCR, and assess its overlap with Mild Cognitive Impairment, Prefrailty, and Frailty, in a cohort of older Scottish adults without dementia.

methodsIn this longitudinal prospective study, we classified 690 participants (mean [SD] age 76.3 [0.8] years; wave 3) of the Lothian Birth Cohort 1936 (LBC1936) into non-MCR or MCR groups. We examined their baseline (age 69.5 [0.8] years; wave 1) risk factors for MCR at waves 3, 4, and 5 (6, 9, and 12 years later respectively).

resultsMCR prevalence rate ranged from 5.3% to 5.7% across the three waves. The presence of MCR was associated with older baseline age (6 and 9 years later), lower occupational socioeconomic status (6 years later), and worse scores in a range of tests of executive function (6, 9 and 12 years later). Approximately 46% of the MCR group also had Mild Cognitive Impairment, and almost everyone in the MCR group had either Prefrailty or Frailty.

conclusionsThe prevalence of MCR in this Scottish cohort is lower than the pooled global average, possibly reflecting the general good health of the LBC cohort. However, it is higher than the prevalence in two neighbouring countries' cohorts, which may reflect the younger average ages of those cohorts. Future LBC1936 research should assess the risk factors associated with MCR to validate previous findings and analyse novel predictive factors, particularly socioeconomic status.

Indexed as

Cognitive DysfunctionDementiaFrailtyAgedCognitionHumansIndependent LivingPrevalenceProspective StudiesRisk FactorsScotlandSyndromedementiaFrailtyMild Cognitive ImpairmentMotoric Cognitive Riskslow gaitsubjective cognitive complaint

Identifiers

PMID36200618
PMCPMC9828770
OpenAlexW4300819173

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.