Evidence map›Paper›PMID 36200577›Full record

ArticleHead & neck2023

Disparities in head and neck cancer incidence and trends by race/ethnicity and sex.

Angela L Mazul, Smrithi Chidambaram, Jose P Zevallos, Sean T Massa

Abstract read
In one paragraph

Article in Head & neck, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Racioethnic disparities in comorbidities and outcomes following head and neck oncologic surgery.World journal of otorhinolaryngology - head and neck surgery · 2025
    Article
  11. Disparities in Care for Patients with Head and Neck Cancer.Surgical oncology clinics of North America · 2024
    Review
  12. Examination of Predictors of Pain at 12 Months Postdiagnosis in Head and Neck Cancer Survivors.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2023
    Observational
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Angela L MazulDepartment of Otolaryngology-Head and Neck Surgery, Washington University School of Medicine, St. Louis, Missouri, USA.
Smrithi ChidambaramDepartment of Otolaryngology-Head and Neck Surgery, Washington University School of Medicine, St. Louis, Missouri, USA.ORCID https://orcid.org/0000-0001-5650-8821
Jose P ZevallosDepartment of Otolaryngology-Head and Neck Surgery, Washington University School of Medicine, St. Louis, Missouri, USA.ORCID https://orcid.org/0000-0002-9111-6767
Sean T MassaDepartment of Otolaryngology-Head and Neck Surgery, Saint Louis University School of Medicine, St. Louis, Missouri, USA.ORCID https://orcid.org/0000-0003-2015-9855

Funding

Washington University Institute of Clinical and Translational Sciences (TL1)TL1TR002344 · NCATS · WASHINGTON UNIVERSITY · PI Jay F. Piccirillo · 2017 to 2026
$8.5M
Development of a Four-Class, Molecular Subtyping Diagnostic for HPV-negative Head and Neck CancerR01CA211939 · NCI · WASHINGTON UNIVERSITY · PI HAYES, DAVID N, ZEVALLOS, JOSE P. · 2017 to 2021
$2.3M
Integrating social and molecular determinants of HPV-associated cancersK01MD013897 · NIMHD · WASHINGTON UNIVERSITY · PI MAZUL, ANGELA LIU · 2020 to 2023
$519k
NCATS NIH HHS TL1 TR002344NCATS NIH HHS TL1TR002344NCI NIH HHS R01 CA211939NIMHD NIH HHS K01 MD013897
6 · The paper itself

Abstract

backgroundThe epidemiology of head and neck cancer (HNC) sites differ substantially. This study compares HNC incidence trends by site and demographic subgroups.

methodsWe used the U.S. Cancer Statistics Public Use Database to calculate HNC incidence rates per 100 000. We assessed trends with annual percent change (APC) longitudinally from 2001 to 2017.

resultsThe oropharyngeal cancer incidence APC decreased from 4.38% (95% CI: 3.6, 5.1) to 2.93% (2.5, 3.3) in 2008 among White males. Oral cavity cancer incidence rose in Other race males (APC 2.5% [1.6, 3.36]) and White females (APC: 0.96% [0.7, 1.2]). Although decreasing (APC: -1.15% [-1.48, -0.83]), laryngeal cancer incidence remained disproportionately high among Black males.

conclusionsNotable incidence trends occurred in non-White groups at non-oropharyngeal sites. With parity of smoking rates by race, differing sexual behaviors, and shifting demographics by race and sex, future studies of HNC trends should consider stratifying analyses to understand health disparities.

Indexed as

Head and Neck NeoplasmsOropharyngeal NeoplasmsBlack PeopleEthnicityFemaleHumansIncidenceMaledemographic disparitiesepidemiologyhead and neck cancerincidenceotolaryngology

Identifiers

PMID36200577
PMCPMC9742317

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.