Evidence map›Paper›PMID 36200491›Full record

ArticleEchocardiography (Mount Kisco, N.Y.)2022

Full and simplified assessment of left ventricular diastolic function in covid-19 patients admitted to ICU: Feasibility, incidence, and association with mortality.

Luigi La Via, Veronica Dezio, Cristina Santonocito, Marinella Astuto, Andrea Morelli, Stephen Huang, Antoine Vieillard-Baron, Filippo Sanfilippo

Open access · hybridAbstract read
In one paragraph

Article in Echocardiography (Mount Kisco, N.Y.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
7.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 45 citations in OpenAlex.

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  4. Left Ventricular Diastolic Dysfunction in the Critically Ill: The Rubik's Cube of Echocardiography.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Luigi La ViaDepartment of Anaesthesia and Intensive Care, "Policlinico-San Marco" University Hospital, Catania, Italy.
Veronica DezioDepartment of Anaesthesia and Intensive Care, "Policlinico-San Marco" University Hospital, Catania, Italy.
Cristina SantonocitoDepartment of Anaesthesia and Intensive Care, "Policlinico-San Marco" University Hospital, Catania, Italy.
Marinella AstutoDepartment of Anaesthesia and Intensive Care, "Policlinico-San Marco" University Hospital, Catania, Italy.
Andrea MorelliDepartment Clinical Internal, Anesthesiological and Cardiovascular Sciences, University of Rome, "La Sapienza", Policlinico Umberto Primo, Roma, Italy.
Stephen HuangIntensive Care Medicine, Nepean Hospital, The University of Sydney, Sydney, Australia.
Antoine Vieillard-BaronService de Médecine Intensive Réanimation, Assistance Publique-Hôpitaux de Paris, University Hospital Ambroise Paré, Boulogne-Billancourt, France.
Filippo SanfilippoDepartment of Anaesthesia and Intensive Care, "Policlinico-San Marco" University Hospital, Catania, Italy.
Hôpital Ambroise-Paré · FRNepean Hospital · AUPoliclinico Umberto I · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeLeft ventricular diastolic dysfunction (LVDD) is associated with poor outcomes in the intensive care unit (ICU). Nonetheless, precise reporting of LVDD in COVID-19 patients is currently lacking and assessment could be challenging.

methodsWe performed an echocardiography study in COVID-19 patients admitted to ICU with the aim to describe the feasibility of full or simplified LVDD assessment and its incidence. We also evaluated the association of LVDD or of single echocardiographic parameters with hospital mortality.

resultsBetween 06.10.2020 and 18.02.2021, full diastolic assessment was feasible in 74% (n = 26/35) of patients receiving a full echocardiogram study. LVDD incidence was 46% (n = 12/26), while the simplified assessment produced different results (incidence 81%, n = 21/26). Nine patients with normal function on full assessment had LVDD with simplified criteria (grade I = 2; grade II = 3; grade III = 4). Nine patients were hospital-survivors (39%); the incidence of LVDD (full assessment) was not different between survivors (n = 2/9, 22%) and non-survivors (n = 10/17, 59%; p = .11). The E/e' ratio lateral was lower in survivors (7.4 [3.6] vs. non-survivors 10.5 [6.3], p = .03). We also found that s' wave was higher in survivors (average, p = .01).

conclusionIn a small single-center study, assessment of LVDD according to the latest guidelines was feasible in three quarters of COVID-19 patients. Non-survivors showed a trend toward greater LVDD incidence; moreover, they had significantly worse s' values (all) and higher E/e' ratio (lateral).

Indexed as

COVID-19Ventricular Dysfunction, LeftDiastoleFeasibility StudiesHeart MurmursHumansIncidenceIntensive Care UnitsVentricular Function, Lefte’E/e’ ratioguidelinessystolic functiontissue Doppler

Identifiers

PMID36200491
PMCPMC9827986
OpenAlexW4302292821

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.