Evidence map›Paper›PMID 36200221›Full record

ArticlePhysiological reports2022

Probing cellular health at the muscle level-Multi-frequency bioimpedance in Parkinson's disease.

Marko Celicanin, Adrian Paul Harrison, Jack Kvistgaard Olsen, Lise Korbo, Annemette Løkkegård, Charlotte Bjerg Petersen, Bente Danneskiold-Samsøe, Hartwig Roman Siebner, Tihomir Ilic, Else Marie Bartels

Open access · goldAbstract read
In one paragraph

Article in Physiological reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Marko CelicaninDepartment of Neurology, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Copenhagen, Denmark.ORCID 0000-0003-0603-1142
Adrian Paul HarrisonFaculty of Health and Medical Sciences, University of Copenhagen, IVH, PAS (Excitable Tissues & Biomechanics), Copenhagen, Denmark.ORCID 0000-0002-6495-5629
Jack Kvistgaard OlsenThe Parker Institute, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Copenhagen, Denmark.
Lise KorboDepartment of Neurology, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Copenhagen, Denmark.
Annemette LøkkegårdDepartment of Neurology, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Copenhagen, Denmark.
Charlotte Bjerg PetersenDepartment of Neurology, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Copenhagen, Denmark.
Bente Danneskiold-SamsøeThe Parker Institute, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Copenhagen, Denmark.
Hartwig Roman SiebnerDepartment of Neurology, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Copenhagen, Denmark.
Tihomir IlicDepartment of Neurophysiology, Medical Faculty of Military Medical Academy, University of Defense, Belgrade, Serbia.
Else Marie BartelsDepartment of Neurology, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Copenhagen, Denmark.ORCID 0000-0001-9302-9678
Frederiksberg Hospital · DKUniversity of Copenhagen · DKMilitary Medical Academy · RS

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bioimpedance (mfBIA) non-invasively assesses cellular muscle health. Our aim was to explore whether mfBIA captures abnormal cellular muscle health in patients with Parkinson's Disease (PD) and how such changes are modulated with the use of Parkinson's medication. In patients with PD (n = 20) mfBIA measurements were made of biceps brachii, triceps, and extensor carpi radialis longus muscles of the more affected arm whilst at rest, using a mobile mfBIA device (IMPEDIMED, Australia). mfBIA and assessment of motor symptoms were performed in a pragmatic off-medication state, as well as one and 3 h after oral intake of 200 mg levodopa. Age and sex-matched healthy subjects (HC; n = 20) served as controls. PD and HC mfBIA parameters were compared by applying an unpaired two-tailed adjusted t-test and ANOVA with Tukey's correction for multiple comparisons (p ≤ 0.05). The PD group consisted of 13 men (71 ± 17 years) and 7 women (65 ± 7 years). Independent of medication, internal (R

Indexed as

Parkinson DiseaseArmFemaleForearmHumansLevodopaMaleMuscle, SkeletalLevodopabioimpedancemulti-frequencymusclesmuscle tonusParkinson's disease

Identifiers

PMID36200221
PMCPMC9535347
OpenAlexW4302287337

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.