Evidence map›Paper›PMID 36200125›Full record

ArticleRSC advances2022

Utility of green chemistry for native spectrofluorimetric quantification of darolutamide as a modern anti-neoplastic drug in its market form and biological fluids.

Hesham Salem, Amany Abdelaziz, Mai R Mekawy, Mohamed M Mahmoud, Kerolos Wissa, Doaa Fisal, Mahmoud A Abdelmajed

Abstract read
In one paragraph

Article in RSC advances, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hesham SalemPharmaceutical Chemistry Department, Faculty of Pharmacy, Deraya University New Minia Egypt h_salem_eg@yahoo.com hesham.salem@deraya.edu.eg.ORCID https://orcid.org/0000-0002-6467-849X
Amany AbdelazizPharmaceutical Chemistry Department, Faculty of Pharmacy, Deraya University New Minia Egypt h_salem_eg@yahoo.com hesham.salem@deraya.edu.eg.
Mai R MekawyFaculty of Pharmacy, Deraya University New Minia Egypt.
Mohamed M MahmoudFaculty of Pharmacy, Deraya University New Minia Egypt.
Kerolos WissaFaculty of Pharmacy, Deraya University New Minia Egypt.
Doaa FisalFaculty of Pharmacy, Deraya University New Minia Egypt.
Mahmoud A AbdelmajedPharmaceutical Chemistry Department, Faculty of Pharmacy, Deraya University New Minia Egypt h_salem_eg@yahoo.com hesham.salem@deraya.edu.eg.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A simple, new, green, and sensitive approach was established and validated for assay of the recently approved antineoplastic medication; darolutamide (DAR) in its authentic form, pharmaceutical formulation, and biological fluids fluorimetrically. This experiment relied on the native fluorescence of the cited drug and detects the ideal solvent utilized throughout the approach. The proposed approach was validated regarding linearity, accuracy, and precision. The calibration graph showed linearity over the range of 0.1-2.0 μg mL

Identifiers

PMID36200125
PMCPMC9442801

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.