Evidence map›Paper›PMID 36200003›Full record

ArticleJournal of diabetes research2022

Diabetes Mellitus and Clinical Outcomes in Carotid Artery Revascularization Using Second-Generation, MicroNet-Covered Stents: Analysis from the PARADIGM Study.

Adam Mazurek, Anna Borratynska, Urszula Gancarczyk, Lukasz Czyz, Martyna Sikorska, Lukasz Tekieli, Bartosz Sobien, Marcin Jakiel, Mariusz Trystula, Tomasz Drazkiewicz and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of diabetes research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Adam MazurekJagiellonian University, Department of Cardiac & Vascular Diseases, John Paul II Hospital, Krakow, Poland.ORCID https://orcid.org/0000-0001-6476-805X
Anna BorratynskaJohn Paul II Hospital, Neurology Outpatient Department, Krakow, Poland.
Urszula GancarczykJagiellonian University, Department of Cardiac & Vascular Diseases, John Paul II Hospital, Krakow, Poland.
Lukasz CzyzJagiellonian University, Department of Cardiac & Vascular Diseases, John Paul II Hospital, Krakow, Poland.
Martyna SikorskaJagiellonian University, Department of Cardiac & Vascular Diseases, John Paul II Hospital, Krakow, Poland.
Lukasz TekieliJagiellonian University, Department of Cardiac & Vascular Diseases, John Paul II Hospital, Krakow, Poland.ORCID https://orcid.org/0000-0002-3431-1013
Bartosz SobienJagiellonian University, Department of Cardiac & Vascular Diseases, John Paul II Hospital, Krakow, Poland.
Marcin JakielJagiellonian University, Department of Cardiac & Vascular Diseases, John Paul II Hospital, Krakow, Poland.ORCID https://orcid.org/0000-0003-3862-0187
Mariusz TrystulaJohn Paul II Hospital, Department of Vascular Surgery, Krakow, Poland.ORCID https://orcid.org/0000-0002-9667-5082
Tomasz DrazkiewiczJohn Paul II Hospital, Department of Vascular Surgery, Krakow, Poland.
Piotr PodolecJagiellonian University, Department of Cardiac & Vascular Diseases, John Paul II Hospital, Krakow, Poland.ORCID https://orcid.org/0000-0001-6101-2935
Piotr MusialekJagiellonian University, Department of Cardiac & Vascular Diseases, John Paul II Hospital, Krakow, Poland.ORCID https://orcid.org/0000-0001-9300-4833
Jagiellonian University · PLJohn Paul II Hospital · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Carotid artery stenting (CAS) using conventional (single-layer) stents is associated with worse clinical outcomes in diabetes mellitus (DM) vs. non-DM patients: an effect driven largely by lesion-related adverse events. CAS outcomes with MicroNet-covered stents (MCS) in diabetic patients have not been evaluated. Aim: To compare short- and long-term clinical outcomes and restenosis rate in DM vs. non-DM patients with carotid stenosis treated using MCS. Materials and Methods: In a prospective study in all-comer symptomatic and increased-stroke-risk asymptomatic carotid stenosis, 101 consecutive patients (age 51-86 years, 41% diabetics) underwent 106 MCS-CAS. Clinical outcomes and duplex ultrasound velocities were assessed periprocedurally and at 30 days/12 months. Results: Baseline characteristics of DM vs. non-DM patients were similar except for a higher prevalence of recent cerebral symptoms in DM. Type 1 and type 1+2 plaques were more prevalent in DM patients (26.7% vs. 9.8%, Conclusions: MCS may offset the adverse impact of DM on periprocedural, 30-day, and 12-month clinical complications of CAS and minimize the risk of in-stent restenosis. In this increased-stroke-risk cohort, adverse event rate was low both in DM and non-DM. Further larger-scale clinical datasets including extended follow-ups are warranted.

Indexed as

Carotid StenosisDiabetes MellitusStrokeAgedAged, 80 and overAngioplastyCarotid ArteriesHumansMiddle AgedProspective StudiesRetrospective StudiesRisk FactorsStentsTime FactorsTreatment Outcome

Identifiers

PMID36200003
PMCPMC9529505
OpenAlexW4297103145

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.