Evidence map›Paper›PMID 36199979›Full record

ArticleJournal of tissue engineering

Soft substrates direct stem cell differentiation into the chondrogenic lineage without the use of growth factors.

Tosca Roncada, Roxane Bonithon, Gordon Blunn, Marta Roldo

Open access · goldAbstract read
In one paragraph

Article in Journal of tissue engineering. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
7.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 48 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Tosca RoncadaSchool of Pharmacy and Biomedical Sciences, University of Portsmouth, Portsmouth, UK.ORCID https://orcid.org/0000-0002-8114-0595
Roxane BonithonSchool of Mechanical and Design Engineering, University of Portsmouth, Portsmouth, UK.ORCID https://orcid.org/0000-0002-4252-0894
Gordon BlunnSchool of Pharmacy and Biomedical Sciences, University of Portsmouth, Portsmouth, UK.
Marta RoldoSchool of Pharmacy and Biomedical Sciences, University of Portsmouth, Portsmouth, UK.ORCID https://orcid.org/0000-0003-2242-7761
University of Portsmouth · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mesenchymal stem cells (MSCs) hold great promise for the treatment of cartilage related injuries. However, selectively promoting stem cell differentiation

Indexed as

Alginatecartilage regenerationhydrogelsmechanobiologystiffness

Identifiers

PMID36199979
PMCPMC9528007
OpenAlexW4302763206

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.