ArticleInternational journal of women's health2022
Characteristics of the Gut Microbiota in Japanese Patients with Premenstrual Syndrome.
Article in International journal of women's health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed, 1 citations in OpenAlex.
- Hormonal Imbalance and Gut Dysbiosis: Emerging Perspectives in Women's Health.Probiotics and antimicrobial proteins · 2026Review
- Dietary patterns are associated with premenstrual symptoms: a cross-sectional study among women from Central Europe.Scientific reports · 2026Article
- Efficacy of Gut Microbiome-Targeted Interventions on Mental Health Symptoms in Women Across Key Hormonal Life Stages: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.Healthcare (Basel, Switzerland) · 2025Review
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Authors and funding
7 authors.
Funding
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Abstract
Purpose: The present study aimed to characterize the gut microbiota of individuals with premenstrual syndrome. Patients and Methods: The gut microbiota of 24 Japanese women with PMS (PMS group) and 144 healthy Japanese women (control group) were compared. Analysis of the α- and β-diversities and the gut microbial composition at the genus level were performed using 16S rRNA gene sequence data obtained from stool samples. Results: A significant difference in age was observed between the PMS and control groups; however, no significant difference was observed in BMI. The α-diversity measured using the Simpson index was significantly higher in the PMS group than the control group. Visualization of the β-diversity using non-metric multidimensional scaling and permutational multivariate analysis of variance (PERMANOVA) showed that the distance of the gut microbiota between the PMS and control groups is significantly different. Furthermore, a significant difference in the composition of the gut microbiota was observed between the PMS and control groups. At the genus level, the abundances of Conclusion: These results suggest that the PMS group possesses a characteristic gut microbiota. In particular,
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