Evidence map›Paper›PMID 36199871›Full record

ArticleRSC advances2022

Synthesis and antibacterial activity studies

Fen-Fen Yang, Ming-Shan Shuai, Xiang Guan, Mao Zhang, Qing-Qing Zhang, Xiao-Zhong Fu, Zong-Qin Li, Da-Peng Wang, Meng Zhou, Yuan-Yong Yang and 3 more

Open access · goldAbstract read
In one paragraph

Article in RSC advances, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 10 citations in OpenAlex.

  1. Advances in microbial biosynthesis of indirubin.Chinese herbal medicines · 2026
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Fen-Fen YangState Key Laboratory of Functions and Applications of Medicinal Plants, School of Pharmacy, and Engineering Research Center for the Development and Application of Ethnic Medicine and TCM (Ministry of Education), Guizhou Medical University Guiyang 550004 People's Republic of China zhaoyl05@126.com zhaoyonglong@gmc.edu.cn 378122847@qq.com.
Ming-Shan ShuaiState Key Laboratory of Functions and Applications of Medicinal Plants, School of Pharmacy, and Engineering Research Center for the Development and Application of Ethnic Medicine and TCM (Ministry of Education), Guizhou Medical University Guiyang 550004 People's Republic of China zhaoyl05@126.com zhaoyonglong@gmc.edu.cn 378122847@qq.com.
Xiang GuanState Key Laboratory of Functions and Applications of Medicinal Plants, School of Pharmacy, and Engineering Research Center for the Development and Application of Ethnic Medicine and TCM (Ministry of Education), Guizhou Medical University Guiyang 550004 People's Republic of China zhaoyl05@126.com zhaoyonglong@gmc.edu.cn 378122847@qq.com.
Mao ZhangState Key Laboratory of Functions and Applications of Medicinal Plants, School of Pharmacy, and Engineering Research Center for the Development and Application of Ethnic Medicine and TCM (Ministry of Education), Guizhou Medical University Guiyang 550004 People's Republic of China zhaoyl05@126.com zhaoyonglong@gmc.edu.cn 378122847@qq.com.
Qing-Qing ZhangState Key Laboratory of Functions and Applications of Medicinal Plants, School of Pharmacy, and Engineering Research Center for the Development and Application of Ethnic Medicine and TCM (Ministry of Education), Guizhou Medical University Guiyang 550004 People's Republic of China zhaoyl05@126.com zhaoyonglong@gmc.edu.cn 378122847@qq.com.
Xiao-Zhong FuState Key Laboratory of Functions and Applications of Medicinal Plants, School of Pharmacy, and Engineering Research Center for the Development and Application of Ethnic Medicine and TCM (Ministry of Education), Guizhou Medical University Guiyang 550004 People's Republic of China zhaoyl05@126.com zhaoyonglong@gmc.edu.cn 378122847@qq.com.
Zong-Qin LiDepartment of Neurology Sichuan Mianyang 404 Hospital Mianyang 621000 People's Republic of China.
Da-Peng WangKey Laboratory of Environmental Pollution Monitoring and Disease Control, Ministry of Education, Guizhou Medical University Guiyang 550025 People's Republic of China.
Meng ZhouState Key Laboratory of Functions and Applications of Medicinal Plants, School of Pharmacy, and Engineering Research Center for the Development and Application of Ethnic Medicine and TCM (Ministry of Education), Guizhou Medical University Guiyang 550004 People's Republic of China zhaoyl05@126.com zhaoyonglong@gmc.edu.cn 378122847@qq.com.
Yuan-Yong YangState Key Laboratory of Functions and Applications of Medicinal Plants, School of Pharmacy, and Engineering Research Center for the Development and Application of Ethnic Medicine and TCM (Ministry of Education), Guizhou Medical University Guiyang 550004 People's Republic of China zhaoyl05@126.com zhaoyonglong@gmc.edu.cn 378122847@qq.com.ORCID https://orcid.org/0000-0003-1878-6614
Ting LiuState Key Laboratory of Functions and Applications of Medicinal Plants, School of Pharmacy, and Engineering Research Center for the Development and Application of Ethnic Medicine and TCM (Ministry of Education), Guizhou Medical University Guiyang 550004 People's Republic of China zhaoyl05@126.com zhaoyonglong@gmc.edu.cn 378122847@qq.com.
Bin HeState Key Laboratory of Functions and Applications of Medicinal Plants, School of Pharmacy, and Engineering Research Center for the Development and Application of Ethnic Medicine and TCM (Ministry of Education), Guizhou Medical University Guiyang 550004 People's Republic of China zhaoyl05@126.com zhaoyonglong@gmc.edu.cn 378122847@qq.com.ORCID https://orcid.org/0000-0001-6884-6166
Yong-Long ZhaoState Key Laboratory of Functions and Applications of Medicinal Plants, School of Pharmacy, and Engineering Research Center for the Development and Application of Ethnic Medicine and TCM (Ministry of Education), Guizhou Medical University Guiyang 550004 People's Republic of China zhaoyl05@126.com zhaoyonglong@gmc.edu.cn 378122847@qq.com.ORCID https://orcid.org/0000-0002-2183-5344
Guiyang Medical University · CNSichuan Mianyang 404 Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multi-drug-resistant microbial pathogens are a serious global health problem. New compounds with antibacterial activity serve as good candidates for developing novel antibacterial drugs which is very urgent and important. In this work, based on the unique scaffold of indirubin, an active ingredient of traditional Chinese medicine formulation Danggui Luhui Wan, we synthesized 29 indirubin-3'-monoximes and preliminarily evaluated their antibacterial activities. The antibacterial activity results demonstrated that the synthesized indirubin-3'-monoximes 5a-5z and 5aa-5ad displayed good potency against

Identifiers

PMID36199871
PMCPMC9438470
OpenAlexW4294286460

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.